+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Advances in the researches of genomic characterization and molecular detection of Middel East respiratory syndrome coronavirus



Advances in the researches of genomic characterization and molecular detection of Middel East respiratory syndrome coronavirus



Zhonghua Yu Fang Yi Xue Za Zhi 49(5): 461-464



Middle east respiratory syndrome coronavirus (MERS-CoV) was recently identified as a novel human coronavirus known to infect human with high mortality. It belongs to C clade of the betacoronavirus shown the similar genomic structure as other human coronaviruses.To date, some different subtypes of the viral genome were identified but its origin was unclear. Some evidences indicated it maybe came from the bats or dromedary. And series of molecular detection methods have been established and applied in lab and clinic.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 057147556

Download citation: RISBibTeXText

PMID: 26081714


Related references

Proficiency testing for the detection of Middle East respiratory syndrome coronavirus demonstrates global capacity to detect Middle East respiratory syndrome coronavirus. Journal of Medical Virology 90(12): 1827-1833, 2018

Assessing the Detection of Middle East Respiratory Syndrome Coronavirus IgG in Suspected and Proven Cases of Middle East Respiratory Syndrome Coronavirus Infection. Viral Immunology 30(9): 649-653, 2017

Development of Middle East Respiratory Syndrome Coronavirus vaccines - advances and challenges. Human Vaccines and Immunotherapeutics 14(2): 304-313, 2018

Origins and pathogenesis of Middle East respiratory syndrome-associated coronavirus: recent advances. F1000research 6: 1628, 2017

Genomic sequencing and analysis of the first imported Middle East Respiratory Syndrome Coronavirus (MERS CoV) in China. Science China. Life Sciences 58(8): 818-820, 2015

Coronaviruses: severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus in travelers. Current Opinion in Infectious Diseases 27(5): 411-417, 2014

Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study. Lancet 382(9909): 1993-2002, 2013

Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV). Journal of Biological Chemistry 291(17): 9218-9232, 2016

Lack of detection of Middle East respiratory syndrome coronavirus in mild and severe respiratory infections in Catalonia, northeastern Spain. New Microbes and new Infections 2(1): 27-28, 2014

Molecular advances in severe acute respiratory syndrome-associated coronavirus (SARS-CoV). Genomics Proteomics and Bioinformatics 1(4): 247-262, 2003

Molecular advances in severe acute respiratory syndrome-associated coronavirus (SARS-CoV). Genomics Proteomics and Bioinformatics 1(4): 247-262, 2003

Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: implications for the origin of the novel Middle East respiratory syndrome coronavirus. Journal of Virology 87(15): 8638-8650, 2013

Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. Mbio 3(6):, 2012

Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion. Journal of Virology 90(19): 8924-8933, 2016

Biochemical Characterization of Middle East Respiratory Syndrome Coronavirus Helicase. Msphere 1(5):, 2016