+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Antifungal activity of extracts and isolated compounds from Buchenavia tomentosa on Candida albicans and non-albicans

Antifungal activity of extracts and isolated compounds from Buchenavia tomentosa on Candida albicans and non-albicans

Future Microbiology 10(6): 917-927

This study aimed to evaluate the antifungal activity of Buchenavia tomentosa extract and bioactive compounds on six Candida species. The antimicrobial activity of extract was evaluated using standard strains and clinical isolates. Cytotoxicity was tested in order to evaluate cell damage caused by the extract. Extract was chemically characterized and the antifungal activity of its compounds was evaluated. Extract showed antifungal activity on Candida species. Candida non-albicans were more susceptible than Candida albicans. Low cytotoxicity for extract was observed. The isolated compounds presented antifungal activity at least against one Candida spp. and all compounds presented antifungal effect on Candida glabrata. Extracts from Buchenavia tomentosa showed promising antifungal activity on Candida species with low cytotoxicity. Gallic acid, corilagin and ellagic acid showed promising inhibitory activity on Candida glabrata.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 057212347

Download citation: RISBibTeXText

PMID: 26059616

DOI: 10.2217/fmb.15.20

Related references

Antimicrobial activity of Buchenavia tetraphylla against Candida albicans strains isolated from vaginal secretions. Pharmaceutical Biology 55(1): 1521-1527, 2017

Potent Antifungal Activity of Pure Compounds from Traditional Chinese Medicine Extracts against Six Oral Candida Species and the Synergy with Fluconazole against Azole-Resistant Candida albicans. Evidence-Based Complementary and Alternative Medicine 2012: 106583, 2012

Effects of Acetone Fraction From Buchenavia tomentosa Aqueous Extract and Gallic Acid on Candida albicans Biofilms and Virulence Factors. Frontiers in Microbiology 9: 647, 2018

Potent antifungal activity of extracts and pure compound isolated from pomegranate peels and synergism with fluconazole against Candida albicans. Research in Microbiology 161(7): 534-540, 2010

Antifungal activity of some plant extracts against Candida albicans. Buletinul Universitatii de Stiinte Agricole si Medicina Veterinara Cluj Napoca Seria Agricultura 61: 394, 2005

Antifungal activity of plant extracts against Candida albicans. American Journal of Chinese Medicine 25(2): 181-184, 1997

Antifungal activity of a Candida albicans GGTase I inhibitor-alanine conjugate. Inhibition of Rho1p prenylation in C. albicans. Bioorganic and Medicinal Chemistry Letters 13(11): 1935-1937, 2003

Antifungal activity of plant extracts against Pityrosporum ovale and Candida albicans. Korean Journal of Pharmacognosy 34(4): 303-307, 2003

Synergistic mutual potentiation of antifungal activity of Zuccagnia punctata Cav. and Larrea nitida Cav. extracts in clinical isolates of Candida albicans and Candida glabrata. Phytomedicine 22(6): 666-678, 2015

Antifungal activity of some medicinal plant extracts against Candida albicans and Cryptococcus neoformans. Acta Horticulturae (597): 217-221, 2003

Beziehungen zwischen Antimykotikum-Konzentration und Kontaktzeit bei der Wirkung von 5-Fluorzytosin, Bifonazol und BAY N 7133 auf Candida albicans : Relations between the Concentration and the Contact-Time in the Antifungal Activity of 5-Fluorcytosine, Bifonazole and BAY N 7133 to Candida albicans. Mycoses 27(9): 436-442, 1984

Evaluation of antifungal activity of medicinal plant extracts against oral Candida albicans and proteinases. Mycopathologia 172(2): 117-124, 2011

Evaluation of the antifungal activity of olive leaf aqueous extracts against Candida albicans PTCC-5027. Current Medical Mycology 1(4): 37-39, 2015

Pharmacoeconomic analysis of antifungal therapy for primary treatment of invasive candidiasis caused by Candida albicans and non-albicans Candida species. Bmc Infectious Diseases 17(1): 481, 2017

QSAR modeling of the antifungal activity against Candida albicans for a diverse set of organic compounds. Bioorganic and Medicinal Chemistry 16(14): 7055-7069, 2008