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Association of neutrophil-lymphocyte ratio with impaired aortic elasticity in newly diagnosed and never-treated hypertensive patients

Association of neutrophil-lymphocyte ratio with impaired aortic elasticity in newly diagnosed and never-treated hypertensive patients

Blood Pressure Monitoring 20(3): 127-131

The aim of our study was to investigate the relationship between neutrophil-to-lymphocyte ratio (NLR) and aortic elasticity in patients with newly diagnosed essential hypertension (HT). A total of 101 patients with newly diagnosed and untreated essential HT and 54 healthy control patients were enrolled. Aortic stiffness (β) index, aortic strain and aortic distensibility (AoD) were measured with formulas by using transthoracic echocardiography and office blood pressure obtained by sphygmomanometer data. NLR was calculated using complete blood count. Patients with HT had significantly higher NLR compared with the healthy control group (2.49±0.77 vs. 1.80±0.65, P<0.001). In addition, there were significant differences between the HT and healthy control groups in β index (12.7±7.35 vs. 6.97±3.3, P<0.001) and AoD (3.0±1.54 vs. 4.85±1.35, P<0.001). There was also a statistically significant correlation between NLR and β index (r=0.727, P<0.001) and AoD (r=-0.606, P<0.001) parameters in hypertensive patients. Our results showed that in patients with newly diagnosed and untreated essential HT, increased NLR has been significantly linked to impaired aortic elastic properties.

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Accession: 057256254

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PMID: 25563436

DOI: 10.1097/mbp.0000000000000104

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