+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Association of neutrophil-lymphocyte ratio with impaired aortic elasticity in newly diagnosed and never-treated hypertensive patients



Association of neutrophil-lymphocyte ratio with impaired aortic elasticity in newly diagnosed and never-treated hypertensive patients



Blood Pressure Monitoring 20(3): 127-131



The aim of our study was to investigate the relationship between neutrophil-to-lymphocyte ratio (NLR) and aortic elasticity in patients with newly diagnosed essential hypertension (HT). A total of 101 patients with newly diagnosed and untreated essential HT and 54 healthy control patients were enrolled. Aortic stiffness (β) index, aortic strain and aortic distensibility (AoD) were measured with formulas by using transthoracic echocardiography and office blood pressure obtained by sphygmomanometer data. NLR was calculated using complete blood count. Patients with HT had significantly higher NLR compared with the healthy control group (2.49±0.77 vs. 1.80±0.65, P<0.001). In addition, there were significant differences between the HT and healthy control groups in β index (12.7±7.35 vs. 6.97±3.3, P<0.001) and AoD (3.0±1.54 vs. 4.85±1.35, P<0.001). There was also a statistically significant correlation between NLR and β index (r=0.727, P<0.001) and AoD (r=-0.606, P<0.001) parameters in hypertensive patients. Our results showed that in patients with newly diagnosed and untreated essential HT, increased NLR has been significantly linked to impaired aortic elastic properties.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 057256254

Download citation: RISBibTeXText

PMID: 25563436

DOI: 10.1097/mbp.0000000000000104


Related references

Evaluation of the neutrophil-lymphocyte ratio in newly diagnosed nondiabetic hypertensive patients with ascending aortic dilatation. Blood Pressure Monitoring 21(4): 238-243, 2017

OP-031 The Relationship Between Monocyte/HDL Cholesterol Ratio and Aortic Elasticity in Newly-Diagnosed Hypertensive Patients. American Journal of Cardiology 115: S13-S14, 2015

Prognostic meaning of neutrophil to lymphocyte ratio (NLR) and lymphocyte to monocyte ration (LMR) in newly diagnosed Hodgkin lymphoma patients treated upfront with a PET-2 based strategy. Annals of Hematology 97(6): 1009-1018, 2018

A Novel Marker of Impaired Aortic Elasticity in Never Treated Hypertensive Patients: Monocyte/High-Density Lipoprotein Cholesterol Ratio. Acta Cardiologica Sinica 33(1): 41-49, 2017

Neutrophil to lymphocyte ratio (NLR) improves the risk assessment of ISS staging in newly diagnosed MM patients treated upfront with novel agents. Annals of Hematology 94(11): 1875-1883, 2015

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio before chemotherapy as potential prognostic factors in patients with newly diagnosed epithelial ovarian cancer. Esmo Open 1(2): E000039, 2016

Prognostic significance of peripheral blood absolute lymphocyte count and derived neutrophil to lymphocyte ratio in patients with newly diagnosed extranodal natural killer/T-cell lymphoma. Cancer Management and Research Volume 11: 4243-4254, 2019

Relationship between neutrophil/lymphocyte ratio and epicardial fat tissue thickness in patients with newly diagnosed hypertension. Journal of International Medical Research 46(3): 940-950, 2018

Relationship between neutrophil-lymphocyte ratio and insulin resistance in newly diagnosed type 2 diabetes mellitus patients. Bmc Endocrine Disorders 15: 9, 2015

Relationship between Thrombotic Events and Peripheral Neutrophil-to-lymphocyte Ratio in Patients with Newly Diagnosed Essential Thrombocythemia. Zhongguo Shi Yan Xue Ye Xue Za Zhi 27(2): 534-538, 2019

The relationship between neutrophil lymphocyte ratio with urinary protein and albumin excretion in newly diagnosed patients with type 2 diabetes. American Journal of the Medical Sciences 347(3): 217-220, 2014

Evaluation of neutrophil-to-lymphocyte ratio in newly diagnosed patients receiving borte- zomib-based therapy for multiple myeloma. Cancer Biomarkers 22(1): 43-48, 2018

Prognostic value of baseline absolute lymphocyte concentration and neutrophil/lymphocyte ratio in dogs with newly diagnosed multi-centric lymphoma. Veterinary and Comparative Oncology 13(4): 337-347, 2016

Comparative effects of nebivolol and metoprolol on red cell distribution width and neutrophil/lymphocyte ratio in patients with newly diagnosed essential hypertension. Journal of Cardiovascular Pharmacology 62(4): 388-393, 2014

The prognostic impact of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio in patients with advanced colorectal cancer treated with first-line chemotherapy. Przeglad Gastroenterologiczny 13(3): 218-222, 2018