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Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters



Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters



Chemical Reviews 116(12): 7330-7396



This Review summarizes the advances in the construction of all-carbon quaternary stereocenters via catalytic enantioselective desymmetrization of prochiral and meso-compounds, highlights the power and potential of this strategy in the total synthesis of natural products and biologically active compounds, and outlines the synthetic opportunities still available.

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Accession: 057364511

Download citation: RISBibTeXText

PMID: 27251100

DOI: 10.1021/acs.chemrev.6b00094


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