+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Chemical Composition and Antimicrobial Activity of the Essential Oil and Methanol Extract of Hypericum aegypticum subsp. webbii (Spach) N. Robson



Chemical Composition and Antimicrobial Activity of the Essential Oil and Methanol Extract of Hypericum aegypticum subsp. webbii (Spach) N. Robson



Chemistry and Biodiversity 13(4): 427-436



Hypericum aegypticum subsp. webbii is an evergreen shrub spread in Mediterranean part of central and southeastern Europe. The chemical composition and antimicrobial activity of the essential oil and MeOH extract of H. aegypticum subsp. webbii were investigated. The monoterpenes α-pinene (63.4 - 68.5%) and β-pinene (16.9 - 17.0%) were main compounds in the volatile oil from aerial parts. In the cluster analysis, the essential oil of H. aegypticum subsp. webbii was separated and chemically different from the oil of other subspecies of H. aegypticum as well as other Hypericum species from Greece. SIMPER analysis revealed that α-pinene (24.79%) was the component that contributed the most to differences between all oils. Also, there was extremely high overall dissimilarity between three subspecies of H. aegypticum. MeOH extract of aerial parts of H. aegypticum subsp. webbii contained flavonoids rutin (56.4 ± 0.9 mg/g), hyperoside and quercetin, and phenolic acids chlorogenic and caffeic acid, while naphthodianthrones were not detected. The antimicrobial activity of essential oil was moderate (MIC from 100 to >200 μg/ml), while MeOH extract inhibited the growth of Gram-positive bacteria Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, and Micrococcus luteus (MIC 50 - 100 μg/ml), more pronounced than the extract of H. perforatum (MIC 200 - >200 μg/ml).

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 057393281

Download citation: RISBibTeXText

PMID: 26923468

DOI: 10.1002/cbdv.201500119


Related references

Antiinflammatory and antioxidant activity of Hypericum rumeliacum Boiss subsp apollinis Robson Strid methanol extract. Phytotherapy Research: 6, 766-771, 2008

Antiinflammatory and antioxidant activity of Hypericum rumeliacum Boiss. subsp. apollinis (Boiss. & Heldr.) Robson & Strid methanol extract. PhytoTherapy Research 22(6): 766-771, 2008

Aromatic profiling of wild and rare species growing in Turkey: Hypericum aviculariifolium Jaub. and Spach subsp. depilatum (Freyn and Bornm.) Robson var. depilatum and Hypericum pruinatum Boiss. and Bal. Natural Product Research 27(2): 100-107, 2013

Chemical composition, antimicrobial and antibiofilm activity of the essential oil and methanol extract of the Mediterranean cypress (Cupressus sempervirens L.). Bmc Complementary and Alternative Medicine 14: 179, 2014

Chemical composition, antioxidant and antimicrobial activity of the essential oil and methanol extract of the Egyptian lemongrass Cymbopogon proximus Stapf. Grasas y Aceites 62(1): 55-61, 2011

The case of Hypericum rochelii Griseb. & Schenk and Hypericum umbellatum A. Kern. essential oils: chemical composition and antimicrobial activity. Journal of Pharmaceutical and Biomedical Analysis 77: 145-148, 2013

The case of Hypericum rochelii Griseb Schenk and Hypericum umbellatum A Kern essential oils Chemical composition and antimicrobial activity. Journal of Pharmaceutical and Biomedical Analysis 77: 145-148, 2013

Antioxidant and antiproliferative activity of Hypericum hircinum L. subsp. majus (Aiton) N. Robson essential oil. Natural Product Research 27(10): 862-868, 2013

Composition and antimicrobial activity of the essential oil of Hypericum rumeliacum subsp. apollinis (Boiss. & Heldr.). PhytoTherapy Research 17(2): 152-154, 2003

Composition and antimicrobial activity of the essential oil and extract of Hypericum elongatum. 2007

Chemical composition and antimicrobial and antioxidant activities of the essential oil and methanol extract of Hippomarathrum microcarpum (Bieb.) from Turkey. Journal of Agricultural and Food Chemistry 55(3): 937-942, 2007

Chemical composition and in vitro anticancer, antimicrobial and antioxidant activities of essential oil and methanol extract from Rumex nervosus. Natural Product Research 33(17): 2554-2559, 2019

Chemical composition, antioxidant, anticholinesterase, antimicrobial and antibiofilm activities of essential oil and methanolic extract of Anthemis stiparum subsp. sabulicola (Pomel) Oberpr. Microbial Pathogenesis 119: 233-240, 2018

Studies on the antioxidant activity of the essential oil and methanol extract of Marrubium globosum subsp. globosum (lamiaceae) by three different chemical assays. Bioresource Technology 99(10): 4239-4246, 2008

Chemical composition of Hypericum richeri subsp. grisebachii essential oil from Croatia. Natural Product Communications 8(2): 231-233, 2013