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Clinical benefits of pitavastatin: focus on patients with diabetes or at risk of developing diabetes



Clinical benefits of pitavastatin: focus on patients with diabetes or at risk of developing diabetes



Future Cardiology 12(4): 449-466



Despite attaining LDL-cholesterol targets, many patients with diabetes remain at risk of developing cardiovascular events. In addition, treatment with statins has been associated with a slight but significant increased risk of development of diabetes, particularly with high-intensity statins. Pitavastatin is a moderate- to high-intensity statin that effectively reduces LDL-cholesterol levels. Pitavastatin provides a sustained increase of HDL-cholesterol levels that may exhibit a neutral or positive effect on glucose metabolism, may not increase the risk of new-onset diabetes, may exhibit positive effects on renal function and urinary albumin excretion and the risk of drug-drug interactions is low. Therefore, it seems that pitavastatin should preferentially be considered in the treatment of dyslipidemia in diabetic patients or at risk of developing diabetes.

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Accession: 057420415

Download citation: RISBibTeXText

PMID: 27076402

DOI: 10.2217/fca-2016-0018


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