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Complete genome sequence of Lactobacillus plantarum LZ227, a potential probiotic strain producing B-group vitamins



Complete genome sequence of Lactobacillus plantarum LZ227, a potential probiotic strain producing B-group vitamins



Journal of Biotechnology 234: 66-70



B-group vitamins play an important role in human metabolism, whose deficiencies are associated with a variety of disorders and diseases. Certain microorganisms such as Lactic acid bacteria (LAB) have been shown to have capacities for B-group vitamin production and thus could potentially replace chemically synthesized vitamins for food fortification. A potential probiotic strain named Lactobacillus plantarum LZ227, which was isolated from raw cow milk in this study, exhibits the ability to produce B-group vitamins. Complete genome sequencing of LZ227 was performed to gain insights into the genetic elements involved in B-group vitamin production. The genome of LZ227 contains a circular 3,131,750-bp chromosome, three circular plasmids and two predicted linear plasmids. LZ227 also contains gene clusters for biosynthesis of both riboflavin and folate. This genome sequence provides a basis for further elucidation of its molecular genetics and probiotic functions, and will facilitate its applications as starter cultures in food industry.

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Accession: 057477102

Download citation: RISBibTeXText

PMID: 27480344

DOI: 10.1016/j.jbiotec.2016.07.020


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