+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Components of the Frailty Phenotype in Relation to the Frailty Index: Results From the Toulouse Frailty Platform

Components of the Frailty Phenotype in Relation to the Frailty Index: Results From the Toulouse Frailty Platform

Journal of the American Medical Directors Association 16(10): 855-859

The frailty phenotype proposed by Fried and colleagues is a widely used frailty screening instrument, consisting of 5 components: weight loss, exhaustion, low grip strength, slow gait speed, and low physical activity. Although equally considered in the computation of the frailty phenotype score, each of the components may present a specific and different weight in clinical practice. The objective of this study was to estimate the weight of each frailty phenotype component in terms of age-related deficit accumulation, defined according to the frailty index (FI) proposed by Rockwood and colleagues. Cross-sectional study. Data were used from 484 frail older adults admitted to a geriatric day hospital unit of the Toulouse University Hospital. The outcome measure was a 35-item FI based on data routinely collected as part of a clinical assessment. Descriptive statistics and linear regression analyses were used to determine which components of the frailty phenotype were most strongly associated with the FI. The mean age of the participants was 83.2 (SD 6.0). All components of the frailty phenotype were significantly associated with the FI, but the magnitude of the associations varied. Linear regression analyses, adjusted for age, sex, and educational level showed that slow gait speed was the most informative component (B = 0.129, P < .001) and weight loss was the least informative component (B = 0.027, P = .037). The combination of slow gait speed and low physical activity was the most strongly associated with the FI (B = 0.144, P < .001). Of the 5 components of the phenotype, slow gait speed seems to be the key indicator of frailty.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 057480319

Download citation: RISBibTeXText

PMID: 25979777

DOI: 10.1016/j.jamda.2015.04.007

Related references

Frailty prevalence and factors associated with the Frailty Phenotype and Frailty Index: Findings from the North West Adelaide Health Study. Australasian Journal on Ageing 37(2): 120-126, 2017

Operationalization of a frailty index using routine data from the Toulouse Frailty Clinic. Geriatrics and Gerontology International 15(4): 519-520, 2016

Comparing Approaches to Measure Frailty in Medicare Data: Deficit-Accumulation Frailty Index Versus Phenotypic Frailty. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 73(7): 989-990, 2018

Large retrospective analysis on frailty assessment in primary care: electronic Frailty Index versus frailty coding. BMJ Health and Care Informatics 26(1): 0, 2019

Identifying frailty: do the Frailty Index and Groningen Frailty Indicator cover different clinical perspectives? a cross-sectional study. Bmc Family Practice 14: 64, 2013

Correlates of frailty phenotype and frailty index and their associations with clinical outcomes. HIV Medicine 18(10): 764-771, 2017

Comparison and Clinical Applications of the Frailty Phenotype and Frailty Index Approaches. Interdisciplinary Topics in Gerontology and Geriatrics 41: 74-84, 2016

Frailty phenotype and frailty index are associated with distinct neuromuscular electrophysiological characteristics in men. Experimental Physiology 2019, 2019

Association Between Frailty and Components of the Frailty Phenotype With Modifiable Risk Factors and Antiretroviral Therapy. Journal of Infectious Diseases 215(6): 933-937, 2017

Frailty prevalence and associated factors in the Mexican health and aging study: A comparison of the frailty index and the phenotype. Experimental Gerontology 79: 55-60, 2017

Frailty Index and Frailty Phenotype in elderly patients with cancer. Acta Oncologica 55(5): 644-646, 2017

Prevalence and outcomes of frailty in Korean elderly population: comparisons of a multidimensional frailty index with two phenotype models. Plos One 9(2): E87958, 2014

Frailty Phenotype and Deficit Accumulation Frailty Index in Predicting Recovery After Transcatheter and Surgical Aortic Valve Replacement. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2018, 2018

Frailty phenotype, frailty index and risk of mortality in Chinese elderly population- Rugao longevity and ageing study. Archives of Gerontology and Geriatrics 80: 115-119, 2018

Frailty in NHANES: Comparing the frailty index and phenotype. Archives of Gerontology and Geriatrics 60(3): 464-470, 2015