EurekaMag
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Diagnostic accuracy of diffusion-weighted MRi for differentiation of cervical cancer and benign cervical lesions at 3.0T: Comparison with routine MRi and dynamic contrast-enhanced MRi


Diagnostic accuracy of diffusion-weighted MRi for differentiation of cervical cancer and benign cervical lesions at 3.0T: Comparison with routine MRi and dynamic contrast-enhanced MRi



Journal of Magnetic Resonance Imaging: Jmri 42(4): 1094-1099



ISSN/ISBN: 1053-1807

PMID: 25824638

DOI: 10.1002/jmri.24894

To compare the diagnostic accuracy of routine magnetic resonance imaging (MRI) (T1 WI and T2 WI), diffusion-weighted MRI (DWI), and DCE-MRI (dynamic contrast-enhanced MRI) at 3.0T for differentiation of cervical cancer and benign cervical lesions. A cohort of 75 cervical cancer patients, 26 cervical leiomyoma patients, 22 patients with cervical polyps consecutively underwent pelvic MRI scanning on a 3T MR unit. Two radiologists independently evaluated images at three imaging settings; routine MRI alone, DWI combined with routine MRI (DWI+routine MRI), and DCE-MRI. The apparent diffusion coefficients (ADCs) were calculated from b 0, 600 s/mm(2) and b 0, 1000 s/mm(2). DWI+routine MRI was significantly better than routine MRI and obtained high accuracy (0.95); the diagnostic performance was not significantly different between DWI+routine MRI and DCE-MRI. Reader agreement was excellent for both DWI+routine MRI (κ, 0.90) and DCE-MRI (κ, 0.92). The ADCs of cervical cancer were significantly lower than those of benign cervical lesions at both ADC maps (P = 0.0001). The diagnostic accuracy was not different at both ADC maps (P = 0.375). For differentiation of cervical cancer and benign cervical lesions, unenhanced MRI with combined diffusion-weighted and routine MRI (DWI+routine MRI) at 3T can provide accurate information and may be preferable to DCE.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 057611876

Download citation: RISBibTeXText

Related references

Endometrial cancer with cervical stromal invasion: diagnostic accuracy of diffusion-weighted and dynamic contrast enhanced MR imaging at 3T. European Radiology 27(5): 1867-1876, 2017

Comparison of the diagnostic accuracy of contrast-enhanced MRi and diffusion-weighted MRi in the differentiation between uterine leiomyosarcoma / smooth muscle tumor with uncertain malignant potential and benign leiomyoma. Journal of Magnetic Resonance Imaging: Jmri 43(2): 333-342, 2016

Added value of diffusion-weighted MRi in detection of cervical cancer recurrence: comparison with morphologic and dynamic contrast-enhanced MRi sequences. Diagnostic and Interventional Radiology 21(5): 368-375, 2015

Comparison of intravoxel incoherent motion diffusion-weighted MR imaging with dynamic contrast-enhanced MRi for differentiating lung cancer from benign solitary pulmonary lesions. Journal of Magnetic Resonance Imaging: Jmri 43(3): 669-679, 2016

Evaluation of international federation of gynecology and obstetrics stage IB cervical cancer: comparison of diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging at 3.0 T. Journal of Computer Assisted Tomography 37(6): 989-994, 2013

Diagnostic performance of diffusion-weighted (DWI) and dynamic contrast-enhanced (DCE) MRi for the differentiation of benign from malignant soft-tissue tumors. Journal of Magnetic Resonance Imaging: Jmri 50(3): 798-809, 2019

Diagnostic accuracy of diffusion weighted imaging & dynamic contrast enhanced Mri in differentiating benign & malignant ovarian masses for optimum possible surgical strategies. Fertility and Sterility 110(4): e132-e133, 2018

Value of diffusion-weighted and dynamic contrast-enhanced MR in predicting parametrial invasion in cervical stromal ring focally disrupted stage IB-IIA cervical cancers. Abdominal Radiology 44(9): 3166-3174, 2019

Intravoxel incoherent motion diffusion-weighted imaging as an adjunct to dynamic contrast-enhanced MRi to improve accuracy of the differential diagnosis of benign and malignant breast lesions. Magnetic Resonance Imaging 36: 175-179, 2017

Diagnostic assessment by dynamic contrast-enhanced and diffusion-weighted magnetic resonance in differentiation of breast lesions under different imaging protocols. Bmc Cancer 14: 366, 2014

Prostate cancer: differentiation of central gland cancer from benign prostatic hyperplasia by using diffusion-weighted and dynamic contrast-enhanced MR imaging. Radiology 257(3): 715-723, 2010

Comparison of the diagnostic accuracy of diffusion-weighted and dynamic contrast-enhanced MRi with 18F-FDG PET/CT to differentiate osteomyelitis from Charcot neuro-osteoarthropathy in diabetic foot. European Journal of Radiology 132: 109299, 2020

Assessment of early response to concurrent chemoradiotherapy in cervical cancer: value of diffusion-weighted and dynamic contrast-enhanced MR imaging. Magnetic Resonance Imaging 32(8): 993-1000, 2014

Multiparametric approach with diffusion-weighted imaging and dynamic contrast-enhanced MRI: a comparison study for differentiating between benign and malignant bone lesions in adults. Clinical Radiology 72(7): 552-559, 2017

Influence of menopausal status on diagnostic accuracy of myometrial invasion in endometrial cancer: diffusion-weighted and dynamic contrast-enhanced MRi at 3 T. Clinical Radiology 70(11): 1260-1268, 2015