EurekaMag
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry


Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry



Comparative Immunology Microbiology and Infectious Diseases 46: 40-46



ISSN/ISBN: 0147-9571

PMID: 27260809

DOI: 10.1016/j.cimid.2016.04.006

Although both domestic sheep (DS) and bighorn sheep (BHS) are affected by similar respiratory bacterial pathogens, experimental and field data indicate BHS are more susceptible to pneumonia. Cross-reactive monoclonal antibodies (mAbs) for use in flow cytometry (FC) are valuable reagents for interspecies comparative immune system analyses. This study describes cross-reactive mAbs that recognize leukocyte differentiation molecules (LDMs) and major histocompatibility complex antigens on DS and BHS leukocytes. Characterization of multichannel eosinophil autofluorescence in this study permitted cell-type specific gating of granulocytes for evaluating LDMs, specifically on neutrophils, by single-label FC. Evaluation of relative abundances of LDMs by flow cytometry revealed greater CD11a, CD11b, CD18 (β2 integrins) and CD 172a (SIRPα) on DS neutrophils and greater CD14 (lipopolysaccharide receptor) on BHS neutrophils. Greater CD25 (IL-2) was identified on BHS lymphocytes following Concavalin A stimulation. While DS and BHS have similar total peripheral blood leukocyte counts, BHS have proportionately more neutrophils.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 057619020

Download citation: RISBibTeXText

Related references

Identification of novel variants of interferon-tau gene in Bighorn sheep (Ovis canadensis mexicana), Pelibuey sheep (Ovis aries) and its expression in hybrid blastocysts (Ovis canadensis x Ovis aries). Canadian Journal of Animal Science 92(3): 275-283, 2012

Differential Susceptibility of Bighorn Sheep (Ovis canadensis) and Domestic Sheep (Ovis aries) Neutrophils to Mannheimia haemolytica Leukotoxin is not due to Differential Expression of Cell Surface CD18. Journal of Wildlife Diseases 53(3): 625-629, 2017

Survival of bighorn sheep (Ovis canadensis) commingled with domestic sheep (Ovis aries) in the absence of Mycoplasma ovipneumoniae. Journal of Wildlife Diseases 48(1): 168-172, 2012

Molecular cloning, characterization and in vitro expression of SERPIN B1 of bighorn sheep (Ovis canadensis) and domestic sheep (Ovis aries), and comparison with that of other species. Veterinary Immunology and Immunopathology 137(3-4): 327-331, 2010

Shared Bacterial and Viral Respiratory Agents in Bighorn Sheep (Ovis canadensis), Domestic Sheep (Ovis aries), and Goats (Capra hircus) in Montana. Veterinary Medicine International 2011: 162520, 2011

Transmission of Mannheimia haemolytica from domestic sheep (Ovis aries) to bighorn sheep (Ovis canadensis): unequivocal demonstration with green fluorescent protein-tagged organisms. Journal of Wildlife Diseases 46(3): 706-717, 2010

The transferrins and hemoglobins of bighorn sheep (Ovis canadensis), dall sheep (Ovis dalli) and mouflon (Ovis musimon). Comparative Biochemistry and Physiology. B Comparative Biochemistry 40(2): 567-570, 1971

Experimental Transmission of Bighorn Sheep Sinus Tumors to Bighorn Sheep (Ovis canadensis canadensis) and Domestic Sheep. Veterinary Pathology 53(6): 1164-1171, 2016

The study of the differences between the anatomy of the bones in mouflons (Ovis musimon L.) and domestic sheep (Ovis aries). Veterinaria (Sarajevo): 334: 477-484, 1984

Transmission of psoroptic mites from bighorn sheep (Ovis canadensis mexicana) to domestic sheep, cattle and rabbits. Journal of Wildlife Diseases 17(3): 381-386, 1981

Psoroptes ovis (Acarina: Psoroptidae) in a Rocky mountain bighorn sheep (Ovis canadensis canadensis) in Idaho. Journal of Wildlife Diseases 21(4): 456-457, 1985

Comparative leukotoxicities of Pasteurella haemolytica isolates from domestic sheep and free-ranging bighorn sheep (Ovis canadensis). Journal of Wildlife Diseases 30(4): 523-528, 1994

Interspecific transfer of IVM IVF-derived red sheep (Ovis orientalis gmelini ) embryos to domestic sheep (Ovis aries ). Theriogenology 44(5): 681-690, 1995

Specific richness in gastrointestinal helminths from the domestic sheep Ovis aries and the Corsican mouflon Ovis musimon introduced onto the Kerguelen archipelago Richesse specifique en helminthes gastro-intestinaux du mouton Ovis aries et du mouflon Ovis musimon introduits dans larchipel de Kerguelen. Vie et Milieu 46(3-4): 305-312, 1996

Richesse spécifique en helminthes gastro-intestinaux du Mouton (Ovis aries) et du Mouflon (Ovis musimon) introduits dans l'archipel de Kerguelen - Specific richness in gastrointestinal helminths from the domestic sheep (Ovis aries) and the Corsican mouflon (Ovis musimon) introduced onto the Kerguelen archipelago. International Mammalogy Congress 46(3-4): 305-312, 1996