+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Exudative Polymorphous Vitelliform Retinopathy: Importance of Early Recognition of the Condition in Patients with Metastatic Melanoma



Exudative Polymorphous Vitelliform Retinopathy: Importance of Early Recognition of the Condition in Patients with Metastatic Melanoma



Ophthalmology and Therapy 5(1): 121-127



Because of the advent of monoclonal antibodies in the treatment of metastatic melanoma, patients with this disease are surviving longer. Early recognition of the disease has therefore become even more important. We present a patient with vitelliform maculopathy, a paraneoplastic retinal maculopathy that is under-recognized. Clinically the retinal findings of serous detachments and pigmentary macular changes are remarkable, while at the same time these patients have surprisingly very few symptoms. This is in contrast to patients who develop melanoma associated retinopathy (MAR) who are very symptomatic early in the disease, but with more subtle retinal findings. Monoclonal antibody treatment is changing the survival rates in metastatic disease making early diagnosis even more important. Exudative polymorphous vitelliform maculopathy (EPVM) needs to be recognized early to avoid delay in diagnosis of metastatic disease.

(PDF emailed within 0-6 h: $19.90)

Accession: 057851230

Download citation: RISBibTeXText

PMID: 26892474

DOI: 10.1007/s40123-016-0044-8


Related references

Acute Exudative Paraneoplastic Polymorphous Vitelliform Maculopathy During Vemurafenib And Pembrolizumab Treatment For Metastatic Melanoma. Retinal Cases & Brief Reports 2017: -, 2017

Acute exudative polymorphous paraneoplastic vitelliform maculopathy in a patient with carcinoma, not melanoma. Archives of Ophthalmology 129(8): 1104-1106, 2011

Paraneoplastic vitelliform retinopathy secondary to metastatic melanoma. Klinische Monatsblatter für Augenheilkunde 232(4): 587-589, 2016

Paraneoplastic vitelliform retinopathy in metastatic cutaneous melanoma. Retinal Cases & Brief Reports 4(3): 246-250, 2010

Paraneoplastic vitelliform retinopathy associated with metastatic choroidal melanoma. Eye (Basingstoke) 21(11): 1436-1437, 2007

Vitelliform retinopathy in metastatic cutaneous melanoma with choroidal involvement. Archives of Ophthalmology 129(11): 1498-1499, 2012

Acute exudative polymorphous vitelliform maculopathy. Transactions of the American Ophthalmological Society 86: 354-366, 1988

Acute exudative polymorphous vitelliform maculopathy. JAMA Ophthalmology 133(3): E143510-E143510, 2015

Acute exudative polymorphous vitelliform maculopathy syndrome. Retina 23(4): 453-462, 2003

Autofluorescence findings in acute exudative polymorphous vitelliform maculopathy. Archives of Ophthalmology 125(2): 274-277, 2007

Acute exudative paraneoplastic polymorphous vitelliform maculopathy in five cases. Ophthalmic Surgery, Lasers & Imaging 43(5): 366-373, 2013

Autoantibodies against bestrophin in a patient with vitelliform paraneoplastic retinopathy and a metastatic choroidal malignant melanoma. Archives of Ophthalmology 126(3): 432-435, 2008

A case of neurosyphilis revealed by acute exudative polymorphous vitelliform maculopathy. Ophthalmic Surgery, Lasers & Imaging Retina 45 Online: E29-E31, 2014

Acute exudative polymorphous vitelliform maculopathy in a young man: a case report. Retinal Cases & Brief Reports 8(3): 200-204, 2015

Intravitreal dexamethasone implant for acute exudative polymorphous vitelliform maculopathy. European Journal of Ophthalmology 24(5): 803-807, 2014