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Detoxification process of tolaasins, lipodepsipeptides, by Microbacterium sp. K3-5



Detoxification process of tolaasins, lipodepsipeptides, by Microbacterium sp. K3-5



Bioscience, Biotechnology, and Biochemistry 82(8): 1455-1458



Tolaasins are antimicrobial lipodepsipeptides. Here, we report the tolaasins-detoxifying properties of Microbacterium sp. K3-5 (K3-5). The detoxification of tolaasins by K3-5 was performed by hydrolyzation of cyclic structure of tolaasins depending on the tolaasin-K3-5 cell interaction. Our data suggest that the cyclic structure of tolaasins is critical for its interaction to target cells.

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Accession: 057851670

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PMID: 29658402

DOI: 10.1080/09168451.2018.1460575


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