EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Fulminant gangrenous ischemic colitis: is it the solely severe type of ischemic colitis?



Fulminant gangrenous ischemic colitis: is it the solely severe type of ischemic colitis?



International Journal of Colorectal Disease (): -



The purposes of the study are to evaluate the characteristics of gangrenous colitis and to identify clinicobiological factors. We performed a retrospective study of 75 patients in whom the diagnosis was made endoscopically and confirmed pathologically, between March 2004 and March 2010 at a tertiary teaching hospital. We classified ischemic colitis into the reversible and irreversible types (gangrenous colitis). The influence of factors, such as medical history, symptoms, physical examination, laboratory abnormalities, endoscopic findings, abnormalities on computed tomography, perioperative issues, complications, and several scoring systems, on gangrenous ischemic changes and mortality was evaluated by univariate and multivariate analyses. Ischemic colitis was classified as gangrenous ischemic type in 19 patients. The sigmoid colon was the most common site of involvement. However, the disease distribution was significantly different between the two groups. Pancolitis was most commonly observed for fulminant gangrenous colitis. A difference between the two groups was detected for several factors: age, mortality, physiologic score, APACHE II, mean arterial pressure at the time of admission, heart rate, albumin level, and sodium bicarbonate concentration. Multivariate analysis indicated four factors predictive of gangrenous colitis: absence of hematochezia, abdominal tenderness, absence of diarrhea, and albumin level. Another multivariate analysis excluding gangrenous change factors for mortality indicated four factors: arterial pH, serum sodium bicarbonate (metabolic acidosis), albumin (<3.0), and arterial oxygenation. Absence of diarrhea and hematochezia, presence of abdominal tenderness, and hypoalbuminemia could be the predictors for development of gangrenous changes of ischemic colitis.

(PDF emailed within 0-6 h: $19.90)

Accession: 057906880

Download citation: RISBibTeXText

PMID: 27838817

DOI: 10.1007/s00384-016-2700-9



Related references

Fulminant gangrenous ischemic colitis: is it the solely severe type of ischemic colitis?. International Journal of Colorectal Disease 27(1): 125-126, 2012

A case of severe gangrenous ischemic colitis following nonsteroidal anti-inflammatory drug intake. Zentralblatt für Chirurgie 129(6): 510-512, 2004

A Case of Perforated Gangrenous-Type Ischemic Colitis after Second Colectomy for Colorectal Cancer. Journal of the Japan Society of Coloproctology 48(1): 57-62, 1995

Ischemic colitis and gangrenous ischemic colitis. Ryoikibetsu Shokogun Shirizu: 154-156, 1994

Non-gangrenous occlusive ischemic colitis. Schweizerische Medizinische Wochenschrift 102(46): 1669-1676, 1972

Clinical study on gangrenous ischemic colitis. Journal of the Japan Society of Coloproctology 55(3): 129-135, 2002

Non gangrenous ischemic colitis of unusual evolution. Revista Espanola de Las Enfermedades del Aparato Digestivo 55(4): 399-404, 1979

Acute gangrenous forms of ischemic colitis. Revista de Chirurgie, Oncologie, Radiologie, O.R.L., Oftalmologie, Stomatologie. Chirurgie 34(6): 421-428, 1985

Gangrenous ischemic colitis. Presentation of 2 cases with fulminating course. Minerva Chirurgica 35(4): 243-250, 1980

A clinical study on four cases of gangrenous ischemic colitis. Journal of the Japan Society of Coloproctology 45(4): 485-490, 1992

What is your diagnosis? Severe ischemic colitis with extensive ischemic necrosis of the right colon with perforation and stercoral peritonitis. Journal de Radiologie 85(7-8): 1077-1079, 2004

Ischemic colitis in the elderly: Predictive factors of gangrenous outcome. Gastroenterologie Clinique et Biologique 23(5): 470-474, 1999

Surgical management of gangrenous ischemic colitis: report of five cases. Diseases of the Colon and Rectum 20(1): 36-39, 1977

Surgical management of gangrenous ischemic colitis report of 5 cases. Diseases of the Colon and Rectum 20(1): 36-39, 1977

A case with gangrenous ischemic colitis complicated aortic dissection. Nihon Shokakibyo Gakkai Zasshi 100(6): 691-696, 2003