+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Growth inhibition and possible mechanism of oleamide against the toxin-producing cyanobacterium Microcystis aeruginosa NIES-843



Growth inhibition and possible mechanism of oleamide against the toxin-producing cyanobacterium Microcystis aeruginosa NIES-843



Ecotoxicology 25(1): 225-233



Oleamide, a fatty acid derivative, shows inhibitory effect against the bloom-forming cyanobacterium Microcystis aeruginosa. The EC50 of oleamide on the growth of M. aeruginosa NIES-843 was 8.60 ± 1.20 mg/L. In order to elucidate the possible mechanism of toxicity of oleamide against M. aeruginosa, chlorophyll fluorescence transient, cellular ultrastructure, fatty acids composition and the transcription of the mcyB gene involved in microcystins synthesis were studied. The results of chlorophyll fluorescence transient showed that oleamide could destruct the electron accepting side of the photosystem II of M. aeruginosa NIES-843. Cellular ultrastructure examination indicated that the destruction of fatty acid constituents, the distortion of thylakoid membrane and the loss of integrity of cell membrane were associated with oleamide treatment and concentration. The damage of cellular membrane increased the release of microcystins from intact cells into the medium. Results presented in this study provide new information on the possible mechanisms involved and potential utilization of oleamide as an algicide in cyanobacterial bloom control.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 057956733

Download citation: RISBibTeXText

PMID: 26547872

DOI: 10.1007/s10646-015-1582-x


Related references

Draft Genome Sequence of Microcystis aeruginosa NIES-98, a Non-Microcystin-Producing Cyanobacterium from Lake Kasumigaura, Japan. Genome Announcements 4(6):, 2016

Improved Draft Genome Sequence of Microcystis aeruginosa NIES-298, a Microcystin-Producing Cyanobacterium from Lake Kasumigaura, Japan. Genome Announcements 6(5):, 2018

Micropeptins from the freshwater cyanobacterium Microcystis aeruginosa (NIES-100). Journal of Natural Products 72(4): 777-781, 2009

Micropeptins 88-A to 88-F, chymotrypsin inhibitors from the cyanobacterium Microcystis aeruginosa (NIES-88). Tetrahedron 54(21): 5545-5556, 1998

Kawaguchipeptin A, a novel cyclic undecapeptide from cyanobacterium Microcystis aeruginosa (NIES-88). Tetrahedron 52(27): 9025-9030, 1996

Two new chymotrypsin inhibitors isolated from the Cyanobacterium Microcystis aeruginosa NIES-88. Journal of Natural Products 68(1): 14-18, 2005

Cryopreservation of a myovirus infecting the toxin-producing cyanobacterium Microcystis aeruginosa. Microbes and Environments 22(3): 297-299, 2007

Microginins 299-A and -B, leucine aminopeptidase inhibitors from the cyanobacterium Microcystis aeruginosa (NIES-299). Tetrahedron 53(30): 10281-10288, 1997

HspA and HtpG enhance thermotolerance in the cyanobacterium, Microcystis aeruginosa NIES-298. Journal of Microbiology and Biotechnology 22(1): 118-125, 2012

Draft genome database construction from four strains (NIES-298, FCY- 26, -27, and -28) of the cyanobacterium Microcystis aeruginosa. Journal of Microbiology and Biotechnology 22(9): 1208-1213, 2012

Inhibitory effects of sanguinarine against the cyanobacterium Microcystis aeruginosa NIES-843 and possible mechanisms of action. Aquatic Toxicology 142-143: 257-263, 2013

Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843. Dna Research 14(6): 247-256, 2007

Growth inhibition and colony formation in the cyanobacterium Microcystis aeruginosa induced by the cyanobacterium Cylindrospermopsis raciborskii. Journal of Plankton Research 34(11): 987-994, 2012

Monosaccharide composition of the outer membrane lipopolysaccharide and O-chain from the freshwater cyanobacterium Microcystis aeruginosa NIES-87. Journal of Applied Microbiology 113(4): 896-903, 2013

Physiological responses of Microcystis aeruginosa NIES-843 (cyanobacterium) under the stress of chitosan modified kaolinite (CMK) loading. Ecotoxicology 21(3): 698-704, 2012