+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

High-risk human papillomavirus cervical infections among healthy women in Guadeloupe

High-risk human papillomavirus cervical infections among healthy women in Guadeloupe

International Journal of Infectious Diseases 41: 13-16

To assess high-risk human papillomavirus (HR HPV) cervical infections and their type distribution among healthy women in Guadeloupe, French West Indies. The details of consecutive non-pregnant women who attended cervical cancer screening and had HPV genotyping performed at the largest pathology laboratory on the island from January 1, 2013 to December 31, 2014 were recorded retrospectively. All women with available HPV genotyping results were included in the study. HR HPV genotyping results for 618 women (median age 42 years) were collected. The overall prevalence rate of HR HPV cervical infection was 36.1% (95% confidence interval (CI) 32.3-40.0%), with the following type distribution: HPV 16 or 18 irrespective of other HPV types, 7.3% (95% CI 5.4-9.6%); other HR HPV types excluding HPV 16 or 18, 28.8% (95% CI 25.3-32.5%). The prevalence rates of overall HR HPV and HR HPV other than 16 or 18 infection increased significantly (p<0.001) with the severity of cytology grade, from 19.7% for normal cytology to 53.8% in atypical squamous cells of undetermined significance (ASC-US) and 67.7% in low-grade squamous intraepithelial lesions (LSIL). The high prevalence rate of HR HPV cervical infection with genotypes other than 16 and 18 in Guadeloupe, irrespective of age and the cytology grade, suggests a potential benefit of the new nine-valent HPV vaccine to prevent HPV infection-related cancers in this Caribbean country.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 057995132

Download citation: RISBibTeXText

PMID: 26597118

DOI: 10.1016/j.ijid.2015.10.012

Related references

High-risk and multiple human papillomavirus infections associated with cervical abnormalities in Japanese women. Cancer Epidemiology, Biomarkers and Prevention 10(1): 45-52, 2001

High-risk cervical human papillomavirus infections among human immunodeficiency virus-positive women in the Bahamas. Plos One 9(1): E85429, 2014

Detection of high-risk human papillomavirus using menstrual blood in women with high-grade squamous intraepithelial lesions or high-risk human papillomavirus infections: A pilot study. Journal of Obstetrics and Gynaecology Research 42(3): 319-324, 2017

Pre-vaccination prevalence of infections with 25 non-high-risk human papillomavirus types among 1,000 Slovenian women in cervical cancer screening. Journal of Medical Virology 86(10): 1772-1779, 2015

HLA-DP is the cervical cancer susceptibility loci among women infected by high-risk human papillomavirus: potential implication for triage of human papillomavirus-positive women. Tumour Biology 37(6): 8019-8025, 2017

Assessment of high-risk human papillomavirus infections using clinician- and self-collected cervical sampling methods in rural women from far western Nepal. Plos One 9(6): E101255, 2015

Prevalence of high--risk human papillomavirus infections in women with benign cervical cytology: a hospital based study from North India. Indian Journal of Cancer 43(3): 110-116, 2006

Combined human papillomavirus DNA and human papillomavirus-like particle serologic assay to identify women at risk for high-grade cervical intraepithelial neoplasia. International Journal of Cancer 120(1): 55-59, 2006

Prevalence of high-risk human papillomavirus infections in healthy Saudi women attending gynecologic clinics in the western region of Saudi Arabia. Annals of Saudi Medicine 33(1): 13-17, 2013

Recurrent human papillomavirus infection detected with the hybrid capture II assay selects women with normal cervical smears at risk for developing high grade cervical lesions: a longitudinal study of 3,091 women. International Journal of Cancer 102(5): 519-525, 2002

Incident cervical infections with high- and low-risk human papillomavirus (HPV) infections among mothers in the prospective Finnish Family HPV Study. Bmc Infectious Diseases 11: 179, 2011

Prevalence and histologic significance of cervical human papillomavirus DNA detected in women at low and high risk for cervical neoplasia. Obstetrics and Gynecology 86(4 Pt 1): 499-503, 1995

Long-term risk of cervical intraepithelial neoplasia grade 3 or worse according to high-risk human papillomavirus genotype and semi-quantitative viral load among 33,288 women with normal cervical cytology. International Journal of Cancer 137(1): 193-203, 2015

Value of high risk human papillomavirus viral load in predicting cervical lesions and triaging for high risk (HR)-HPV-positive women. Zhonghua Zhong Liu Za Zhi 36(4): 316-320, 2014

Epidemiology of acquisition and clearance of cervical human papillomavirus infection in women from a high-risk area for cervical cancer. Journal of Infectious Diseases 180(5): 1415-1423, 1999