In situ remineralisation response of different artificial caries-like enamel lesions to home-care and professional fluoride treatments
Salomão, P.M.A.; Comar, L.ív.P.; Buzalaf, M.íl.A.R.; Magalhães, A.C.
Bmc Oral Health 16: 2
2016
ISSN/ISBN: 1472-6831
PMID: 26746199
DOI: 10.1186/s12903-016-0160-9
Accession: 058084146
Artificial lesions produced by different protocols might directly influence the response to different remineralising treatments. This study compared the response of different artificial caries-like enamel lesions to home-care and professional fluoride based-remineralising treatments in situ. The tested demineralising protocols were methylcellulose- MC gel, polyacrylic acid - PA gel, tetraethyl methylene diphosphanate - TEMDP solution, and acetate- Buffer solution. The lesions were remineralised using an in situ model, following a crossover and double blind design. Twelve subjects wore intra-oral appliances during 3 phases (3 d each): control (C) (saliva); home-care F(-) treatment (FD) (1,100 ppm F(-) dentifrice, 2x1 min/day); and professional (FVD) (22,600 ppm F(-) varnish) plus FD. The de-remineralisation was measured by transverse microradiography-TMR and hardness (surface hardness/cross-sectional hardness, SH/CSH, respectively). For SH, lesions produced by PA gel were the only one showing significant differences among the remineralising treatments (C x FD x FVD); while the TEMDP lesion were not responsive to any fluoride treatment (for both SH/CSH). For TMR, there were no differences among the remineralising treatments, regardless of the type of lesion. Generally, the most responsive lesions to fluoride were the less demineralised lesions (considering hardness: PA gel and Buffer). The type of lesion has influence on the surface remineralisation degree induced by home-care and professional fluoride treatments using this in situ model.