EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Influence of multi-leaf collimator leaf width in radiosurgery via volumetric modulated arc therapy and 3D dynamic conformal arc therapy



Influence of multi-leaf collimator leaf width in radiosurgery via volumetric modulated arc therapy and 3D dynamic conformal arc therapy



Physica Medica 31(3): 293-296



To study the influence of Multileaf Collimator (MLC) leaf width in radiosurgery treatment planning for Volumetric Modulated Arc Therapy (VMAT) and 3D Dynamic Conformal Arc Therapy (3D-DCA). 16 patients with solitary brain metastases treated with radiosurgery via the non-coplanar VMAT were replanned for the 3D-DCA. For each planning technique two MLC leaf width sizes were utilized, i.e. 5 mm and 2.5 mm. These treatment plans were compared using dosimetric indices (conformity, gradient and mean dose for brain tissue) and the normal tissue complication probability (NTCP). An improvement in planning quality for VMAT was observed versus 3D-DCA for any MLC leaf width, mainly with regards to dose conformity and to a lesser extent regards dose gradient. No significant difference was observed for any of both techniques using smaller leaf width. However, dose gradient was improved in favor of the 2.5 mm MLC for either of both techniques (15% VMAT and 10% 3D-DCA); being noticeable for lesions smaller than 10cm(3). Nonetheless, the NTCP index was not significantly affected by variations in the dose gradient index. This, our present study, suggests that the use of an MLC leaf width of 2.5 mm via the noncoplanar VMAT and 3D-DCA techniques provides improvement in terms of dose gradient for small volumes, over those results obtained with an MLC leaf width of 5 mm. The 3D-DCA does also benefit from MLC leaf widths of a smaller size, mainly in terms of conformity.

(PDF emailed within 0-6 h: $19.90)

Accession: 058112961

Download citation: RISBibTeXText

PMID: 25703035

DOI: 10.1016/j.ejmp.2015.01.011



Related references

Time-resolved dose reconstruction by motion encoding of volumetric modulated arc therapy fields delivered with and without dynamic multi-leaf collimator tracking. Acta Oncologica 52(7): 1497-1503, 2014

Clinical significance of multi-leaf collimator positional errors for volumetric modulated arc therapy. RadioTherapy and Oncology 97(3): 554-560, 2011

Evaluation of dosimetric effect caused by slowing with multi-leaf collimator (MLC) leaves for volumetric modulated arc therapy (VMAT). Radiology and Oncology 50(1): 121-128, 2016

A volumetric-modulated arc therapy using sub-conformal dynamic arc with a monotonic dynamic multileaf collimator modulation. Physics in Medicine and Biology 53(22): 6395-6417, 2008

Minimum requirements for commissioning and long-term quality assurance of Elekta multi-leaf collimator for volumetric modulated arc therapy. Radiological Physics and Technology 6(1): 98-106, 2013

A technique for dynamic intensity-modulated radiation therapy of the breast using a multi-leaf collimator. International Journal of Radiation Oncology Biology Physics 36(1 SUPPL ): 221, 1996

Dosimetric study using different leaf-width MLCs for treatment planning of dynamic conformal arcs and intensity-modulated radiosurgery. Medical Physics 32(2): 405-411, 2005

Direct impact analysis of multi-leaf collimator leaf position errors on dose distributions in volumetric modulated arc therapy: a pass rate calculation between measured planar doses with and without the position errors. Physics in Medicine and Biology 56(20): N237-N246, 2012

Feasibility of single-isocenter, multi-arc non-coplanar volumetric modulated arc therapy for multiple brain tumors using a linear accelerator with a 160-leaf multileaf collimator: a phantom study. Journal of Radiation Research 55(5): 1015-1020, 2015

Dosimetric comparison of 25 mm vs 3 mm leaf width micro-multileaf collimator-based treatment systems for intracranial stereotactic radiosurgery using dynamic conformal arcs implications for treatment planning. 2011

Dosimetric comparison of 2.5 mm vs. 3.0 mm leaf width micro-multileaf collimator-based treatment systems for intracranial stereotactic radiosurgery using dynamic conformal arcs: implications for treatment planning. Japanese Journal of Radiology 29(9): 630-638, 2012

Impact of collimator leaf width on stereotactic radiosurgery and 3D conformal radiotherapy treatment plans. International Journal of Radiation Oncology Biology Physics 44(4): 937-945, July 1, 1999

Comparison of volumetric-modulated arc therapy and dynamic conformal arc treatment planning for cranial stereotactic radiosurgery. Journal of Applied Clinical Medical Physics 17(1): 5677-5677, 2016

New possibilities for volumetric-modulated arc therapy using the Agility™ 160-leaf multileaf collimator. Strahlentherapie und Onkologie 190(11): 1066-1074, 2015