+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Iron nanoparticles decorated multi-wall carbon nanotubes modified carbon paste electrode as an electrochemical sensor for the simultaneous determination of uric acid in the presence of ascorbic acid, dopamine and L-tyrosine



Iron nanoparticles decorated multi-wall carbon nanotubes modified carbon paste electrode as an electrochemical sensor for the simultaneous determination of uric acid in the presence of ascorbic acid, dopamine and L-tyrosine



Materials Science and Engineering. C Materials for Biological Applications 57: 328-337



Iron nanoparticles decorated multi-wall carbon nanotubes modified carbon paste electrode (Fe-MWCNTs/MCPE) was prepared by bulk-modification method. The electrochemical impedance spectroscopy (EIS) suggests least charge transfer resistance at the modified electrode. The electrochemical behavior of UA was studied in 0.1M phosphate buffer solution (PBS) of pH3.0 using cyclic voltammetry (CV) while differential pulse voltammetry (DPV) was used for quantification. The spectroelectrochemial study of oxidation of UA at Fe-MWCNTs/MCPE showed a decrease in the absorbance of two peaks with time, which are ascribed to π to π(⁎) and n to π(⁎) transitions. Under optimum condition, the DPV response offered two linear dynamic ranges for UA in the concentration range 7.0×10(-8)M-1.0×10(-6)M and 2.0×10(-6)M-1.0×10(-5)M with detection limit (4.80±0.35)×10(-8)M (S/N=3). The practical analytical application of this sensor was successfully evaluated by determination of spiked UA in clinical samples, such as human blood serum and urine with good percentage recovery. The proposed electrochemical sensor offers a simple, reliable, rapid, reproducible and cost effective analysis of a quaternary mixture of biomolecules containing AA, DA, UA and Tyr which was free from mutual interferences.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 058164250

Download citation: RISBibTeXText

PMID: 26354272

DOI: 10.1016/j.msec.2015.08.003


Related references

Simultaneous determination of ascorbic acid, dopamine, and uric acid using a carbon paste electrode modified with multiwalled carbon nanotubes, ionic liquid, and palladium nanoparticles. Microchimica Acta 181(15-16): 1999-2008, 2014

Multi-walled carbon nanotube modified carbon paste electrode as an electrochemical sensor for the determination of epinephrine in the presence of ascorbic acid and uric acid. Materials Science and Engineering. C Materials for Biological Applications 33(6): 3294-3302, 2013

Simultaneous determination of norepinephrine, uric acid, and ascorbic acid at a screen printed carbon electrode modified with polyacrylic acid-coated multi-wall carbon nanotubes. Biosensors and Bioelectronics 25(10): 2351-2355, 2010

Novel electrochemical sensor based on N-doped carbon nanotubes and Fe3O4 nanoparticles: simultaneous voltammetric determination of ascorbic acid, dopamine and uric acid. Journal of Colloid and Interface Science 432: 207-213, 2014

Electrodeposition of palladium nanoparticles on porous graphitized carbon monolith modified carbon paste electrode for simultaneous enhanced determination of ascorbic acid and uric acid. Sensors and Actuators B: Chemical 218: 280-288, 2015

Nafion/Ni(OH)2 nanoparticles-carbon nanotube composite modified glassy carbon electrode as a sensor for simultaneous determination of dopamine and serotonin in the presence of ascorbic acid. Sensors and Actuators B: Chemical 176: 543-551, 2013

Determination of Ascorbic Acid in the Presence of Uric Acid and Folic Acid by a Nanostructured Electrochemical Sensor Based on a TiO 2 Nanoparticle Carbon Paste Electrode. Analytical Letters 43(16): 2618-2630, 2010

A glassy carbon electrode modified with a nickel(II) norcorrole complex and carbon nanotubes for simultaneous or individual determination of ascorbic acid, dopamine, and uric acid. Microchimica Acta 183(7): 2139-2145, 2016

Synergistic Effect of Graphene and Multiwalled Carbon Nanotubes on a Glassy Carbon Electrode for Simultaneous Determination of Uric Acid and Dopamine in the Presence of Ascorbic Acid. Analytical Letters 48(2): 248-258, 2015

Simultaneous determination of ascorbic acid, acetaminophen and codeine based on multi-walled carbon nanotubes modified with magnetic nanoparticles paste electrode. Materials Science and Engineering. C Materials for Biological Applications 69: 1-11, 2016

Optimization of modified carbon paste electrode with multiwalled carbon nanotube/ionic liquid/cauliflower-like gold nanostructures for simultaneous determination of ascorbic acid, dopamine and uric acid. Materials Science and Engineering. C Materials for Biological Applications 44: 58-68, 2014

Simultaneous electrochemical determination of uric acid, dopamine, and ascorbic acid at single-walled carbon nanohorn modified glassy carbon electrode. Biosensors and Bioelectronics 25(4): 940-943, 2009

Simultaneous determination of ascorbic acid, dopamine and uric acid using a glassy carbon electrode modified with the nickel(II)-bis(1,10-phenanthroline) complex and single-walled carbon nanotubes. Microchimica Acta 183(4): 1401-1408, 2016

A simple ultrasensitive electrochemical sensor for simultaneous determination of gallic acid and uric acid in human urine and fruit juices based on zirconia-choline chloride-gold nanoparticles-modified carbon paste electrode. Biosensors and Bioelectronics 114: 30-36, 2018

Simultaneous determination of ascorbic acid, adrenaline and uric acid at a hematoxylin multi-wall carbon nanotube modified glassy carbon electrode. Sensors and Actuators B: Chemical 143(2): 666-672, 2010