+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Lawsonia intracellularis and Porcine Circovirus type-2 infection in Estonia



Lawsonia intracellularis and Porcine Circovirus type-2 infection in Estonia



Polish Journal of Veterinary Sciences 19(2): 291-301



The present study describes the reasons of post-weaning distress in Estonian pig herds. Here we examined the natural cases of Lawsonia intracellularis and porcine circovirus 2 (PCV2) infection and co-infections. The presence of L. intracellularis in swine herds were tested by PCR and by histopathological methods, whereas PCV2 was detected by real-time-PCR and immunohistochemical stainings. Seven of the 11 investigated herds with signs of post-weaning wasting were infected with L. intracellularis and all 11 herds with PCV2. From the analysed samples 22.2% were infected with L. intracellularis and 25% with PCV2. The results of microbiological studies suggested that the piglets suffered from enteritis and pneumonia. Escherichia coli and Pasteurella multocida often aggravated the process of illness. The frequency of L. intracellularis was high in pigs 7-12 weeks old (18.5-42.7%) and PCV2 infection was too high in pigs 7-12 weeks old (24.8-32.7%). E. coli was often a co-factor with L. intracellularis and PCV2. The primary reasons of post weaning wasting were PCV2 and E. coli, later aggravated by L. intracellularis and other pathogens. Our results indicated that different pathogens have an important role in developing post-weaning wasting. Proliferative intestinal inflammation caused by L. intracellularis is mainly characterised by its localization and morphological findings. The main gross lesions were the enlargement of mesenteric lymph nodes and thickening of the wall of ileum. In post-weaning multi-systemic wasting syndrome there are characteristic histological lesions in lymphoid tissues. They consist of a variable degree of lymphocyte depletion, together with histiocytic and/or multinucleate giant cell infiltration. This basic lymphoid lesions is observable in almost all tissues of a single severely affected animal, including lymph nodes, Peyer's patches and spleen. Sporadically, multifocal coagulative necrosis may be observed.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 058203328

Download citation: RISBibTeXText

PMID: 27487502

DOI: 10.1515/pjvs-2016-0036


Related references

Enteritis associated with Lawsonia intracellularis and porcine circovirus type 2 infection in wild boars in Southern Brazil. Ciencia Rural: 9, 2540-2544. Ef, 2008

Distinction between porcine circovirus type 2 enteritis and porcine proliferative enteropathy caused by Lawsonia intracellularis. Journal of Comparative Pathology 135(4): 176-182, 2006

Investigation of the association of growth rate in grower-finishing pigs with the quantification of Lawsonia intracellularis and porcine circovirus type 2. Preventive Veterinary Medicine 108(1): 63-72, 2013

Experimental reproduction of porcine circovirus type 2 (PCV2)-associated enteritis in pigs infected with PCV2 alone or concurrently with Lawsonia intracellularis or Salmonella typhimurium. Journal of Comparative Pathology 145(2-3): 261-270, 2011

Lawsonia intracellularis infection in horses. Literature review and case report FT Lovak Lawsonia intracellularis fertozese - Irodalmi attekintes es esetismertetes. 2008

Evaluation of porcine ileum models of enterocyte infection by Lawsonia intracellularis. Canadian Journal of Veterinary Research 70(2): 155-159, 2006

Comparison of diagnostic techniques for porcine proliferative enteropathy (Lawsonia intracellularis infection). Journal of Comparative Pathology 129(2/3): 179-185, 2003

Attempted infection of mice, rats and chickens by porcine strains of Lawsonia intracellularis. Australian Veterinary Journal 77(2): 120-122, 1999

Infection of different strains of mice with Lawsonia intracellularis derived from rabbit or porcine proliferative enteropathy. Journal of Comparative Pathology 139(1): 8-15, 2008

Examinations on the incidence of Lawsonia intracellularis and about FT Vingalatok a Lawsonia intracellularis elterjedtsegerol es a fertozotottseget befolyasolo tenyezokrol. 2007

Infection studies on human cell lines with porcine circovirus type 1 and porcine circovirus type 2. Xenotransplantation 11(3): 284-294, 2004

Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents. Official Gazette of the United States Patent & Trademark Office Patents 1220(4): 3512, March 23, 1999

Expression by Lawsonia intracellularis of type III secretion system components during infection. Veterinary Microbiology 139(3-4): 298-303, 2010

Commercially produced spray-dried porcine plasma contains increased concentrations of porcine circovirus type 2 DNA but does not transmit porcine circovirus type 2 when fed to naive pigs. Journal of Animal Science 89(6): 1930-1938, 2011

Porcine proliferative enteropathy and Lawsonia intracellularis. Compendium on continuing education for the practicing veterinarian: 21S53-S59, 1999