+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Left ventricular rotational mechanics in infants with hypoxic ischemic encephalopathy and preterm infants at 36 weeks postmenstrual age: A comparison with healthy term controls

Left ventricular rotational mechanics in infants with hypoxic ischemic encephalopathy and preterm infants at 36 weeks postmenstrual age: A comparison with healthy term controls

Echocardiography 34(2): 232-239

There is a paucity of data on left ventricle (LV) rotational physiology in neonates. We aimed to assess rotational mechanics in infants with hypoxic ischemic encephalopathy (HIE) and premature infants (<32 weeks) at 36 weeks postmenstrual age (PMA) (preterm group) and compare them with healthy term controls (term controls). We also compared the parameters in preterm infants with and without chronic lung disease (CLD). Echocardiography was performed within 48 hours of birth or at 36 weeks PMA. LV basal and apical rotation, twist (and torsion=twist/LV length), twist rate (LVTR), and untwist rate (LVUTR) were measured. One-way ANOVA was used to compare values. There was no difference in gestation (40.0 [39.1-40.3] vs 39.9 [39.0-40.9], P>.05) or birthweight (3.7 [3.4-4.1] vs 3.5 [3.2-3.9], P>.05) between the HIE group (n=16) and term controls (n=30). The preterm group (n=35) had a gestation and weight of 36.0 [34.6-36.3] weeks and 2.3 [2.0-2.4] kg. The HIE group had lower twist, torsion, LVTR, and LVUTR than the other two groups. The preterm group had a more negative (clockwise) basal rotation while the term group had a more positive (counterclockwise) apical rotation. Preterm infants with CLD had higher apical rotation, twist, and torsion when compared to infants without CLD. Infants with HIE have reduced rotational mechanics. Preterm infants at 36 weeks PMA have comparable measurements of twist to term infants. This is achieved by predominant basal rather than apical rotation. Infants with CLD have increased apical rotation.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 058207209

Download citation: RISBibTeXText

PMID: 27933664

DOI: 10.1111/echo.13421

Related references

Left Ventricular Rotational Mechanics in Preterm Infants Less Than 29 Weeks' Gestation over the First Week after Birth. Journal of the American Society of Echocardiography 28(7): 808-17.E1, 2016

Perinatal acidosis and hypoxic-ischemic encephalopathy in preterm infants of 33 to 35 weeks' gestation. Journal of Pediatrics 160(3): 388-394, 2012

Perinatal brain injuries and subsequent epilepsy: a study on intraventricular hemorrhage in preterm infants and hypoxic-ischemic encephalopathy in full-term infants. No to Hattatsu 22(5): 423-428, 1990

Echocardiographic Measurements of Right Ventricular Mechanics in Infants with Bronchopulmonary Dysplasia at 36 Weeks Postmenstrual Age. Journal of Pediatrics 203: 210-217.E1, 2018

Ultrasonic findings in hypoxic-ischemic encephalopathy of preterm and full-term infants. Duodecim; Laaketieteellinen Aikakauskirja 102(2): 103-111, 1986

Hypothermia for hypoxic ischemic encephalopathy in infants > or =36 weeks. Early Human Development 85(10 Suppl.): S49-S52, 2010

State profile in low-risk pre-term infants: a longitudinal study of 7 infants from 32-36 weeks of postmenstrual age. Brain and Development 14(1): 12-17, 1992

Iron status at birth and at 4 weeks in preterm-SGA infants in comparison with preterm and term-AGA infants. Journal of Maternal-Fetal and Neonatal Medicine 25(8): 1474-1478, 2013

Short-term outcomes comparison between preterm infants with and without acute hypoxic respiratory failure attributable to presumed pulmonary hypoplasia after prolonged preterm premature rupture of membranes before 25 gestational weeks. Journal of Maternal-Fetal and Neonatal Medicine 2017: 1-8, 2017

Comparison of left ventricular cardiac dimensions between small and appropriate for gestational age preterm infants below 30 weeks of gestation. Journal of Perinatal Medicine 41(2): 219-226, 2013

Posture of low-risk preterm infants between 32 and 36 weeks postmenstrual age. Developmental Medicine and Child Neurology 31(2): 191-195, 1989

Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy. Early Human Development 125: 1-7, 2018

A case-control study of hypoxic-ischemic encephalopathy in newborn infants at >36 weeks gestation. American Journal of Obstetrics and Gynecology 209(1): 29.E1-29.E19, 2013

Visual function at 35 and 40 weeks' postmenstrual age in low-risk preterm infants. Pediatrics 122(6): E1193-8, 2008

Effect of DHA-containing formula on growth of preterm infants to 59 weeks postmenstrual age. American Journal of Human Biology 11(4): 457-467, 2001