+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Long-term Graft and Patient Survival after Balloon Dilation of Ureteric Stenosis after Renal Transplant: A 23-year Retrospective Matched Cohort Study

Long-term Graft and Patient Survival after Balloon Dilation of Ureteric Stenosis after Renal Transplant: A 23-year Retrospective Matched Cohort Study

Radiology 281(1): 301-310

Purpose To study long-term graft and patient survival after percutaneous ureteroplasty of ureteric stenosis after renal transplantation and to compare the outcomes to those of patients who did not develop ureteric stenosis. Materials and Methods An ethical waiver was obtained for this 23-year retrospective matched cohort study of 52 of 1476 consecutive kidney transplant recipients who developed postoperative ureteric stenosis. Data were collected between January 1990 and December 2012. All patients (mean age, 47 years [range, 23-72 years]; 36 men aged 29-72 years [mean age, 49 years] and 24 women aged 23-68 years [mean age, 42 years]) underwent percutaneous ureteroplasty; recurrent stenosis was managed surgically or by means of long-term ureteric stent placement. Outcomes were compared with those of a matched control group of transplant recipients with no history of ureteric stenosis. Primary outcome measures were death-censored graft failure and all-cause mortality. Secondary outcome measures were the effect of time of stricture onset on graft survival, complications, and risk factors for recurrent stenosis. Kaplan-Meier curves were compared by using log-rank tests, with P < .05 indicative of a statistically significant difference. Results Balloon dilation was technically successful in all 52 strictures, but stenosis recurred in 10 patients and was treated with surgery (n = 5) or long-term stent placement (n = 5). The 10-year graft and patient survival were not significantly different in study versus control groups, with graft survival of 64.5% (95% confidence interval [CI]: 43.4%, 79.4%) versus 76.3% (95% CI: 58.6%, 87.2%), respectively (P = .372), and patient survival of 82.2% (95% CI: 62.9%, 92%) versus 89.9% (95% CI: 74.6%, 96.2%) (P = .632). Subgroup analysis showed that stenosis occurring less than 3 months (10-year graft survival, 59.1%), at least 3 months (10-year graft survival, 67.3%), and at least 6 months (10-year graft survival, 53.0%) after transplantation did not adversely affect graft survival compared with that of the control group (P > .05). Cold ischemia time was longer in those with recurrent stenosis than in control subjects (16.1 vs 8.4 hours, respectively; P = .034). The minor and major complication rates were 13% and 5.7%, respectively, with no 30-day graft loss and patient mortality. Conclusion Long-term graft and patient survival in patients with percutaneous ureteroplasty of transplant ureteric stenosis were not significantly worse than those in a control group. (©) RSNA, 2016.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 058232640

Download citation: RISBibTeXText

PMID: 27018575

DOI: 10.1148/radiol.2016151629

Related references

Long-term Graft and Patient Survival after Percutaneous Angioplasty or Arterial Stent Placement for Transplant Renal Artery Stenosis: A 21-year Matched Cohort Study. Radiology 290(2): 555-563, 2019

Renal function at 1 year after cardiac transplantation rather than acute kidney injury is highly associated with long-term patient survival and loss of renal function - a retrospective cohort study. Transplant International 30(8): 788-798, 2017

Influence of renal function on long-term graft survival and patient survival in renal transplant recipients. Current Medical Research and Opinion 30(2): 235-242, 2014

Former smoking and early and long-term graft outcome in renal transplant recipients: a retrospective cohort study. Transplant International 30(2): 187-195, 2017

A retrospective analysis of long-term graft survival in 61 pediatric renal transplant recipients: a single-center experience. Annals of Transplantation 18: 497-504, 2013

Long-term graft survival in transplant-glomerulonephritis and chronic transplant glomerulopathy A matched pair study. Journal of the American Society of Nephrology 7(9): 1902, 1996

Long-term graft survival with or without donor-specific transfusion in cyclosporine era in one haplo-identical living-related renal transplant recipients beyond the first year: a 19-year experience. Tohoku Journal of Experimental Medicine 197(4): 201-207, 2002

Recurrent urinary tract infections in kidney transplant recipients during the first-year influence long-term graft function: a single-center retrospective cohort study. Journal of Nephrology 32(4): 661-668, 2019

Long-term outcomes of patients treated with primary stenting for transplant renal artery stenosis: a 10-year case cohort study. World Journal of Surgery 36(1): 222-228, 2012

Long-Term Outcomes of Patients Treated with Primary Stenting for Transplant Renal Artery Stenosis A 1-year Case Cohort Study. 2012

Long-term results of percutaneous balloon dilation for discrete subaortic stenosis A 17-year Study. European Heart Journal 23(Abstract Suppl.): 623, August-September, 2002

Long-term results of percutaneous balloon dilation for isolated discrete subaortic stenosis A 17-year study. Circulation 106(19 Suppl.): II 451, 2002

Pregnancy in renal transplant recipients: long-term effect on patient and graft survival. A single-center experience. Transplantation 81(5): 660-664, 2006

Kidney transplant with multiple renal artery grafts from deceased donors: are long-term graft and patient survival compromised?. Progress in Transplantation 22(1): 102-109, 2012

Effect of cyclosporine dose one year post 1 degree cadaveric renal transplant on subsequent rejection , patient survival , graft survival and graft function. Journal of the American Society of Nephrology 4(3): 927, 1993