+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Longterm survival outcomes of patients undergoing treatment with radiofrequency ablation for hepatocellular carcinoma and metastatic colorectal cancer liver tumors



Longterm survival outcomes of patients undergoing treatment with radiofrequency ablation for hepatocellular carcinoma and metastatic colorectal cancer liver tumors



Hpb 18(9): 756-763



We aim to investigate long-term survival outcomes in patients undergoing radiofrequency ablation (RFA), based on our longitudinal 5 and 10 year follow-up data. All patients who underwent RFA for hepatocellular carcinoma (HCC) and colorectal liver metastasis (CLM) between 1999 and 2010. 320 patients were included with oncologic diagnoses of HCC in 122 (38.1%) and CLM in 198 (61.9%). The majority of patients had a single tumor ablation (71% RFA 1 lesion). Minimum 5 year follow-up information was available in 89% patients, with a median follow-up of 115.3 months. In patients with HCC, disease eventually recurred in 73 (64%) patients. In patients with CLM, disease recurrence was ultimately seen in 143 (84.1%) patients. In the HCC group, the 5- and 10-year overall survivals were 38.5% and 23.4%, while in the CLM group, the 5- and 10-year overall survivals were 27.6% and 15%, respectively. The use of RFA as a part of treatment strategy for primary and metastatic liver tumors imparts 10-year overall survivals of >23% and 15%, respectively. This study indicates that long-term survival is possible with RFA treatment.

(PDF emailed within 0-6 h: $19.90)

Accession: 058238047

Download citation: RISBibTeXText

PMID: 27593593

DOI: 10.1016/j.hpb.2016.06.010


Related references

Comparison of Outcomes of Hepatic Resection and Radiofrequency Ablation for Hepatocellular Carcinoma Patients with Multifocal Tumors Meeting the Barcelona-Clinic Liver Cancer Stage A Classification. Journal of the American College of Surgeons 221(5): 951-961, 2016

Ten-year survival of hepatocellular carcinoma patients undergoing radiofrequency ablation as a first-line treatment. World Journal of Gastroenterology 22(10): 2993-3005, 2017

Radiofrequency ablation for hepatocellular carcinoma and metastatic liver tumors: a comparative study. Journal of Surgical Oncology 94(7): 565-571, 2006

Transcatheter Arterial Chemoembolization With or Without Radiofrequency Ablation: Outcomes in Patients With Barcelona Clinic Liver Cancer Stage B Hepatocellular Carcinoma. Ajr. American Journal of Roentgenology 210(4): 891-898, 2018

Tumor Location Influences Oncologic Outcomes of Hepatocellular Carcinoma Patients Undergoing Radiofrequency Ablation. Cancers 10(10), 2018

Therapeutic efficacy comparison of radiofrequency ablation in hepatocellular carcinoma and metastatic liver cancer. Experimental and Therapeutic Medicine 7(4): 897-900, 2014

Survival comparison between surgical resection and percutaneous radiofrequency ablation for patients in Barcelona Clinic Liver Cancer early stage hepatocellular carcinoma. Indian Journal of Gastroenterology 32(4): 253-257, 2014

Recent advances in radiofrequency ablation in the treatment of hepatocellular carcinoma and metastatic liver cancers. Chang Gung Medical Journal 32(1): 22-32, 2009

Radiofrequency ablation of liver metastases improves the survival rate of patients with metastatic colorectal disease. Acta Radiologica 48(3): 250-251, 2007

Radiofrequency ablation in combined treatment of metastatic colorectal liver cancer. Khirurgiia 2017(12): 4-18, 2017

Radiofrequency thermal ablation of synchronous metastatic liver tumors can be performed safely in conjunction with colorectal cancer resection. Cancer Journal 6(Supplement 4): S344-S350, November-December, 2000

A comparison of perioperative outcomes in elderly patients with malignant liver tumors undergoing laparoscopic liver resection versus radiofrequency ablation. Surgical Endoscopy 31(3): 1269-1274, 2016

Postoperative neutrophil-to-lymphocyte ratio change predicts survival of patients with small hepatocellular carcinoma undergoing radiofrequency ablation. Plos One 8(3): E58184, 2013

Meta-Analysis of Long-Term Outcomes in Patients with Colorectal Liver Metastases Undergoing Hepatectomy with or without Radiofrequency Ablation. American Surgeon 84(12): 1913-1923, 2019

Percutaneous radiofrequency ablation guided by contrast-enhanced ultrasound in treatment of metastatic hepatocellular carcinoma after liver transplantation. Asian Pacific Journal of Cancer Prevention 13(8): 3709-3712, 2013