+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Lower urinary tract symptoms and urodynamic findings in children and adults with cerebral palsy: A systematic review



Lower urinary tract symptoms and urodynamic findings in children and adults with cerebral palsy: A systematic review



Neurourology and Urodynamics 36(3): 541-549



To systematically review the scientific literature addressing lower urinary tract symptoms (LUTS) and urodynamic findings in adults and children with Cerebral Palsy (CP). Prognostic factors were also investigated. A systematic research was conducted on the electronic databases PubMed, Web of Science, and CINAHL. Only full text clinical trials which examined the prevalence of LUTS or urodynamic findings in children or adults with CP were eligible. LUTS and urodynamic findings, defined by the International Children's Continence Society, were extracted from the included studies. Pooled average of extracted data was calculated. Studies were scored on methodological and reporting quality using the Dutch Cochrane Checklist, EBRO guidelines, and the Strengthening the Reporting of Observational Studies in Epidemiology Statement (STROBE) checklist. Twenty-seven studies fulfilled selection criteria. Methodological and reporting quality were moderate to low. An average of 55.5% of subjects with CP experience one or more LUTS. Storage symptoms are more common than voiding symptoms due to the high prevalence of neurogenic detrusor overactivity. Patients with voiding symptoms and pelvic floor overactivity are more prone to progress to upper urinary tract dysfunction in adult life. Urodynamic evaluation can direct management. Negative prognostic factors are the spastic subtype with quadriplegic distribution, moderate to severe functional impairment (GMFCS III or higher) and severe cognitive impairment. The significant prevalence of LUTS, risk for deterioration, and the impact of urinary tract symptoms on quality of life and health status warrants the need for evaluation and treatment in further research. Neurourol. Urodynam. 36:541-549, 2017. © 2016 Wiley Periodicals, Inc.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 058245068

Download citation: RISBibTeXText

PMID: 26894322

DOI: 10.1002/nau.22982


Related references

Urinary tract infections and urodynamic findings in children with severe cerebral palsy. Developmental Medicine and Child Neurology (55): 6, 1987

What is a representative voiding pattern in children with lower urinary tract symptoms? Lack of consistent findings in ambulatory and conventional urodynamic tests. Journal of Pediatric Urology 12(3): 154.E1, 2016

α1-Blockers Improve Benign Prostatic Obstruction in Men with Lower Urinary Tract Symptoms: A Systematic Review and Meta-analysis of Urodynamic Studies. European Urology 69(6): 1091-1101, 2016

Uroflowmetry in the management of lower urinary tract symptoms of children and adolescents with cerebral palsy. Journal of Pediatric Urology 10(3): 413-417, 2014

Medical Treatment of Nocturia in Men with Lower Urinary Tract Symptoms: Systematic Review by the European Association of Urology Guidelines Panel for Male Lower Urinary Tract Symptoms. European Urology 72(5): 757-769, 2017

Urodynamic findings in young men with chronic lower urinary tract symptoms. Neurourology and Urodynamics 30(8): 1580-1585, 2011

Symptoms and urodynamic findings in women with dysfunction of the lower urinary tract. Ugeskrift for Laeger 146(15): 1118-1121, 1984

Changes of urodynamic findings and lower urinary tract symptoms after radical prostatectomy. European Urology Suppl.s 7(3): 87, 2008

Detrusor instability in men: Correlation of lower urinary tract symptoms with urodynamic findings. Journal of Urology 166(2): 550-553, 2001

The urodynamic findings in men with lower urinary tract symptoms refractory to alpha-blockers. Journal of Urology 165(5 Suppl.): 300-301, 2001

Urodynamic findings in young nulliparous women with lower urinary tract symptoms. Journal of Urology 167(4 Suppl.): 199, 2002

Urodynamic findings before and after Interstim therapy for refractory lower urinary tract symptoms. Journal of Urology 169(4 Suppl.): 403, 2003

Urodynamic findings in female patients reporting with lower urinary tract symptoms. Journal of Ayub Medical College Abbottabad 21(1): 8-10, 2009

The effects of isolated posterior compartment defects on lower urinary tract symptoms and urodynamic findings. Bju International 97(5): 1024-1026, 2006

Urodynamic findings and lower urinary tract symptoms in multiple sclerosis patients with internuclear ophthalmoplegia. Journal of Urology 161(4 Suppl. ): 277, 1999