+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Macular Thickness Assessment in Patients with Glaucoma and Its Correlation with Visual Fields



Macular Thickness Assessment in Patients with Glaucoma and Its Correlation with Visual Fields



Journal of Current Glaucoma Practice 10(3): 85-90



To determine the relationship between macular thickness (MT) and visual field (VF) parameters, as well as with changes in the retinal nerve fiber layer (RNFL) thickness in patients with glaucoma and ocular hypertension (OH). Cross-sectional statistical analysis of spectral domain optical coherence tomography (SD-OCT) compared with several VF parameters (mean defect - MD and loss variance - LV), in a nonrandom sample of 70 eyes from patients with glaucoma or OH. Statistical analysis was performed using Statistical Package for Social Sciences®. The correlation coefficient used was determined by Spearman correlation and the value of p < 0.05 was considered statistically significant. A significant correlation was seen between VF parameters and decrease in MT (MD: r = -0.363, p = 0.002; LV: r=-0.378, p = 0.001). The results were more significant when we compared the LV in the group with average MT 270 to 300 μm (r = -0.413, p = 0.015). Asymmetry between the superior macula and inferior macula correlated with LV (r = 0.432, p = 0.019) in the group with MT < 270 μm. There was also a significant correlation between thinning of superior-temporal and inferior-temporal RNFL and the decrease of the superior and inferior MT respectively (p < 0.001). Spectral domain optical coherence tomography measurements of retinal thickness in the macula correlate with VF parameters and RNFL parameters in glaucoma patients. This relationship was first demonstrated with static computerized perimetry made with Octopus 101®. These results can be a valuable aid for evaluating and monitoring of glaucoma patients, establishing a correlation between structure and function. Measurements of retinal thickness in the macula may be an additional instrument for early detection of structural changes and its correlation with functional defects. Mota M, Vaz FT, Ramalho M, Pedrosa C, Lisboa M, Kaku P, Esperancinha F. Macular Thickness Assessment in Patients with Glaucoma and Its Correlation with Visual Fields. J Curr Glaucoma Pract 2016;10(3):85-90.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 058254283

Download citation: RISBibTeXText

PMID: 27857487


Related references

Correlation of macular thickness with visual fields in glaucoma patients and suspects. Journal of Glaucoma 23(2): E98-104, 2014

Correlation between peripapillary macular fiber layer thickness and visual acuity in patients with open-angle glaucoma. Clinical Ophthalmology 4: 629-635, 2010

Correlation between macular thickness and glaucomatous visual fields. Journal of Glaucoma 21(8): 505-509, 2013

Correlation of visual functions with macular thickness in primary open angle glaucoma. Oman Journal of Ophthalmology 6(2): 96-98, 2013

Correlation of visual acuity and macular thickness measured by optical coherence tomography in patients with persistent macular edema. Retina 30(7): 1090-1094, 2010

Correlation of retinal nerve fiber layer thickness and visual fields in glaucoma: a broken stick model. American Journal of Ophthalmology 157(5): 953-959, 2014

Simulated visual fields produced from macular RNFLT data in patients with glaucoma. Current Eye Research 38(11): 1133-1141, 2014

Correlation between central corneal thickness and visual field defect, cup to disc ratio and retinal nerve fiber layer thickness in primary open-angle glaucoma patients. Journal of the Medical Association of Thailand 97(7): 751-757, 2015

Regional correlation of macular areas and visual acuity in patients with open-angle glaucoma. Clinical and Experimental Ophthalmology 43(3): 279-282, 2015

Correlation between the nerve fiber layer thickness and visual field in glaucoma patients. Investigative Ophthalmology & Visual Science 36(4): S974, 1995

Correlation of retinal sensitivity, visual acuity and central macular thickness in different types of diabetic macular edema. Chinese Journal of Ophthalmology 49(12): 1081-1088, 2014

The correlation between optical coherence tomographic features and severity of retinopathy, macular thickness and visual acuity in diabetic macular edema. International Ophthalmology 26(3): 93-99, 2006

A 6-month assessment of bimatoprost 0.03% vs timolol maleate 0.5%: hypotensive efficacy, macular thickness and flare in ocular-hypertensive and glaucoma patients. Eye 21(2): 164-168, 2005

Correlation among retinal thickness, optic disc, and visual field in glaucoma patients and suspects: a pilot study. Journal of Glaucoma 12(2): 119-128, 2003

Agreement of observers for assessment of Humphrey visual fields , PROGRESSOR pointwise linear analysis and the Advanced Glaucoma Intervention Study scoring system in detecting progression of visual field loss in glaucoma. IOVS 40(4): S69, March 15, 1999