+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Maghemite based silicone composite for arterial embolization hyperthermia



Maghemite based silicone composite for arterial embolization hyperthermia



Materials Science and Engineering. C Materials for Biological Applications 48: 632-641



Maghemite nanoparticle based silicone composite for application in arterial embolization hyperthermia is developed. It possesses embolization ability, high heating efficiency in alternating magnetic fields and radiopaque property. The initial components of the composite are selected so that the material stays liquid for 20min, providing the opportunity for transcatheter transportation and filling of the tumour vascular system. After this induction period the viscosity increases rapidly and soft embolus is formed which is able to occlude the tumour blood vessels. The composite is thermally stable up to 225°C, displays rubber-elastic properties and has a thermal expansion coefficient higher than that of blood. Maghemite nanoparticles uniformly distributed in the composite provide its rapid heating (tens of °Cmin(-1)) due to Neel magnetization relaxation. Required X-ray contrast of composite is achieved by addition of potassium iodide.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 058254519

Download citation: RISBibTeXText

PMID: 25579966

DOI: 10.1016/j.msec.2014.12.046


Related references

Sr-hexaferrite/maghemite composite nanoparticles-possible new mediators for magnetic hyperthermia. Nanotechnology 19(21): 215705, 2008

Studies on hyperthermia combined with arterial blockade for treatment of tumors: (Part II) effectiveness of hyperthermia combined with arterial embolization using degradable starch microspheres. Oncology Reports 5(3): 705-708, 1998

Studies on the effectiveness of hyperthermia combined with arterial therapeutic blockage in the treatment of tumors part 3. clinical studies on the effectiveness of hyperthermia combined with arterial chemo embolization using degradable starch microspheres dsm. Journal of Japan Society for Cancer Therapy 23(11): 2725-2731, 1988

Hepatic arterial chemotherapy combined with hyperthermia or arterial embolization in unresectable liver tumor. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 15(8 Pt 2): 2590-2595, 1988

Studies on the effectiveness of hyperthermia combined with arterial therapeutic blockage in the treatment of tumors. Part 2. Experimental studies on the effectiveness of hyperthermia combined with arterial embolization using degradable starch microspheres (DSM). Nihon Gan Chiryo Gakkai Shi 23(11): 2717-2724, 1988

Combined hepatic arterial infusion chemotherapy with transcatheter arterial embolization and hyperthermia in primary liver cancer. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 15(8 Pt 2): 2465-2469, 1988

Tumor response to arterial embolization hyperthermia and direct injection hyperthermia in a rabbit liver tumor model. Journal of Surgical Oncology 80(3): 149-156, 2002

Therapeutic arterial embolization and hyperthermia. Bulletin du Cancer 68(3): 295, 1981

Magnetic SiO2 gel microspheres for arterial embolization hyperthermia. Biomedical Materials 5(6): 065010, 2010

Arterial embolization hyperthermia in porcine renal tissue. Journal of Surgical Research 105(2): 209-214, 2002

Acute pulmonary embolism during therapeutic arterial embolization with silicone fluids. Anesthesiology 60(4): 384-385, 1984

Effect of arterial embolization using degradable starch microspheres combined with hyperthermia. Uicc (Union Internationale Contre Le Cancer, International Union Against Cancer) 14th International Cancer Congress, Budapest, Hungary, Aug 21-27, Abstracts, Lectures, Symposia And Free Communications, Vols 1, 2, 3, Late Abstracts, And Register Xvi+479p (Vol 1); Xvi+298p (Vol 2); Xvi+531p (Vol 3); 15p (Late Abstracts); 40p (Register) S Karger Ag: Basel, Switzerland; New York, N Y , Usa; Akademiai Kiado: Budapest, Hungary Paper 1137, 1986

Trans-catheter hepatic arterial injection of lipiodol soluble anti-cancer agent SMANCS and ADR suspension in lipiodol combined with arterial embolization and local hyperthermia for treatment of hepatocellular carcinoma. International Journal of Hyperthermia 7(1): 7, 1991

Magnetic soft siloxane material for arterial embolization and hyperthermia of malignant tumors. Vestnik Rentgenologii i Radiologii .(6): 35-40, 2003