+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Modulation of physiological mirror activity with transcranial direct current stimulation over dorsal premotor cortex



Modulation of physiological mirror activity with transcranial direct current stimulation over dorsal premotor cortex



European Journal of Neuroscience 44(9): 2730-2734



Humans have a natural tendency towards symmetrical movements, which rely on a distributed cortical network that allows for complex unimanual movements. Studies on healthy humans using rTMS have shown that disruption of this network, and particularly the dorsal premotor cortex (dPMC), can result in increased physiological mirror movements. The aim of the present set of experiments was to further investigate the role of dPMC in restricting motor output to the contralateral hand and determine whether physiological mirror movements could be decreased in healthy individuals. Physiological mirror movements were assessed before and after transcranial direct current stimulation (tDCS) over right and left dPMC in three conditions: bilateral, unilateral left and unilateral right stimulation. Mirror EMG activity was assessed immediately before, 0, 10 and 20 min after tDCS. Results show that physiological mirroring increased significantly in the hand ipsilateral to cathodal stimulation during bilateral stimulation of the dPMC, 10 and 20 min after stimulation compared to baseline. There was no significant modulation of physiological mirroring in the hand ipsilateral to anodal stimulation in the bilateral condition or following unilateral anodal or unilateral cathodal stimulation. The present data further implicate the dPMC in the control of unimanual hand movements and show that physiological mirroring can be increased but not decreased with dPMC tDCS.

(PDF emailed within 0-6 h: $19.90)

Accession: 058334343

Download citation: RISBibTeXText

PMID: 27564926

DOI: 10.1111/ejn.13385


Related references

Role of the right dorsal premotor cortex in "physiological" mirror EMG activity. Experimental Brain Research 175(4): 633-640, 2006

Transcranial direct current stimulation of the premotor cortex: effects on hand dexterity. Brain Research 1576(): 52-62, 2015

Anodal transcranial direct current stimulation over premotor cortex facilitates observational learning of a motor sequence. European Journal of Neuroscience 41(12): 1597-1602, 2016

Modulation of cortical activity after anodal transcranial direct current stimulation of the lower limb motor cortex: a functional MRI study. Brain Stimulation 5(4): 462-467, 2013

Cathodal transcranial direct current stimulation (tDCS) applied to the left premotor cortex (PMC) stabilizes a newly learned motor sequence. Behavioural Brain Research 316: 87-93, 2016

No Modulation of Visual Cortex Excitability by Transcranial Direct Current Stimulation. Plos One 11(12): E0167697-E0167697, 2016

The Modulation of Error Processing in the Medial Frontal Cortex by Transcranial Direct Current Stimulation. Neuroscience Journal 2013: 187692-187692, 2013

A novel dual-site transcranial magnetic stimulation paradigm to probe fast facilitatory inputs from ipsilateral dorsal premotor cortex to primary motor cortex. Neuroimage 62(1): 500-509, 2012

The role of the right dorsal premotor cortex in visuomotor learning: a transcranial magnetic stimulation study. Neuroreport 16(15): 1715-1718, 2005

Motor cortex-induced plasticity by noninvasive brain stimulation: a comparison between transcranial direct current stimulation and transcranial magnetic stimulation. Neuroreport 24(17): 973-975, 2014

Bidirectional variability in motor cortex excitability modulation following 1 mA transcranial direct current stimulation in healthy participants. Physiological Reports 4(15): -, 2016

Modulation of human trigeminal and extracranial nociceptive processing by transcranial direct current stimulation of the motor cortex. Cephalalgia 31(6): 661-670, 2011

Focal and bi-directional modulation of lower limb motor cortex using anodal transcranial direct current stimulation. Brain Stimulation 3(1): 42-42, 2010

Modulation of pharyngeal motor cortex by transcranial direct current stimulation (tDCS): A dose response study. 2007

Modulation of Cortical Inhibitory Circuits after Cathodal Transcranial Direct Current Stimulation over the Primary Motor Cortex. Frontiers in Human Neuroscience 10: 30-30, 2016