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Oxidative Heck desymmetrisation of 2,2-disubstituted cyclopentene-1,3-diones

Oxidative Heck desymmetrisation of 2,2-disubstituted cyclopentene-1,3-diones

Chemical Communications 51(19): 4089-4092

Oxidative Heck couplings have been successfully developed for 2,2-disubstituted cyclopentene-1,3-diones. The direct coupling onto the 2,2-disubstituted cyclopentene-1,3-dione core provides a novel expedient way of enantioselectively desymmetrising all-carbon quaternary centres.

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Accession: 058488442

Download citation: RISBibTeXText

PMID: 25665602

DOI: 10.1039/c5cc00407a

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