+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Pathways from maternal depression to young adult offspring depression: an exploratory longitudinal mediation analysis

Pathways from maternal depression to young adult offspring depression: an exploratory longitudinal mediation analysis

International Journal of Methods in Psychiatric Research 26(2):

Maternal depression in the peri-natal period is associated with increased risk for young adult depression in offspring. This study explored mediation of these links via trajectories of child conduct and emotional problems (Strengths and Difficulties Questionnaire) from ages 4-16 years old in data from the Avon Longitudinal Study of Parents and Children cohort (n = 13373). Through gender-specific structural equation models, a composite measure of exposure to early maternal depression (Edinburgh Postnatal Depression Scale), predicted young adult depression at age 18 (Revised Clinical Interview Schedule - distal outcome). Mediational effects were then estimated by testing which parts of joint piecewise latent trajectory models for child/adolescent conduct and emotional problems were associated with both exposure and distal outcome. For girls, only conduct problems in early childhood were consistently indicated to mediate effects of early maternal depression on risk of young adulthood depression. Some evidence for a pathway via changing levels of childhood and adolescent emotional difficulties was also suggested. For boys, by contrast, the differing models gave less consistent findings providing some evidence for a small time-specific indirect effect via early childhood conduct problems. In addition to its practice implications the current methodological application offers considerable potential in exploratory longitudinal developmental mediation studies. © 2016 The Authors International Journal of Methods in Psychiatric Research Published by John Wiley & Sons Ltd.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 058511275

Download citation: RISBibTeXText

PMID: 27469020

DOI: 10.1002/mpr.1520

Related references

Longitudinal pathways from early maternal depression to children's dysregulated representations: a moderated mediation analysis of harsh parenting and gender. Attachment and Human Development 18(1): 46-68, 2016

Maternal depression in childhood and aggression in young adulthood: evidence for mediation by offspring amygdala-hippocampal volume ratio. Journal of Child Psychology and Psychiatry and Allied Disciplines 56(10): 1083-1091, 2015

Maternal depression and family adversity: Linked pathways to offspring depression?. Journal of Psychiatric Research 88: 97, 2017

Older maternal age is associated with depression, anxiety, and stress symptoms in young adult female offspring. Journal of Abnormal Psychology 125(1): 1-10, 2016

Cognitive change in cognitive-behavioural therapy v. pharmacotherapy for adult depression: a longitudinal mediation analysis. Psychological Medicine 49(15): 2626-2634, 2019

Maternal depression and psychiatric outcomes in adolescent offspring: a 13-year longitudinal study. Journal of Affective Disorders 97(1-3): 145-154, 2007

Maternal Depression, Parenting, and Youth Depressive Symptoms: Mediation and Moderation in a Short-Term Longitudinal Study. Journal of Clinical Child and Adolescent Psychology 53 45(3): 279-290, 2016

Antenatal depression predicts depression in adolescent offspring: prospective longitudinal community-based study. Journal of Affective Disorders 113(3): 236-243, 2009

Parental major depression and the risk of depression and other mental disorders in offspring: a prospective-longitudinal community study. Archives of General Psychiatry 59(4): 365-374, 2002

Maternal depression during pregnancy and offspring depression in adulthood: role of child maltreatment. British Journal of Psychiatry 207(3): 213-220, 2015

Association of Maternal and Paternal Depression in the Postnatal Period With Offspring Depression at Age 18 Years. JAMA Psychiatry 76(3): 290-296, 2019

Maternal depression during pregnancy and the postnatal period: risks and possible mechanisms for offspring depression at age 18 years. JAMA Psychiatry 70(12): 1312-1319, 2013

Maternal Postnatal Depression and the Development of Depression in Offspring Up to 16Years of Age. Yearbook of Pediatrics 2013: 416-418, 2013

Maternal postnatal depression and the development of depression in offspring up to 16 years of age. Journal of the American Academy of Child and Adolescent Psychiatry 50(5): 460-470, 2011

The long-term effects of maternal depression: early childhood physical health as a pathway to offspring depression. Journal of Adolescent Health 54(1): 88-93, 2014