Private versus social incentives for pharmaceutical innovation
González, P.; Macho-Stadler, I.és.; Pérez-Castrillo, D.
Journal of Health Economics 50: 286-297
2016
ISSN/ISBN: 1879-1646 PMID: 26944633 DOI: 10.1016/j.jhealeco.2015.12.003
Accession: 058627708
We provide a theoretical framework to contribute to the current debate regarding the tendency of pharmaceutical companies to direct their R&D toward marketing products that are "follow-on" drugs of already existing drugs, rather than toward the development of breakthrough drugs. We construct a model with a population of patients who can be treated with drugs that are horizontally and vertically differentiated. In addition to a pioneering drug, a new drug can be marketed as the result of an innovative process. We analyze physician prescription choices and the optimal pricing decision of an innovative firm. We also characterize the incentives of the innovative firm to conduct R&D activities, disentangling the quest for breakthrough drugs from the firm effort to develop follow-on drugs. Our results offer theoretical support for the conventional wisdom that pharmaceutical firms devote too many resources to conducting R&D activities that lead to incremental innovations.