+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Profiling the immunity status of children with non-polio acute flaccid paralysis who had not received any doses of oral polio vaccine in the South-South region, Nigeria 2011-2014



Profiling the immunity status of children with non-polio acute flaccid paralysis who had not received any doses of oral polio vaccine in the South-South region, Nigeria 2011-2014



Public Health 139: 148-153



To demonstrate the immunity status of children with non-polio acute flaccid paralysis (NP AFP) reported through the AFP surveillance system in the South-South region of Nigeria. A retrospective study was conducted using AFP surveillance data collected routinely between January 2011 and December 2014 by the Disease Surveillance Department of the regional health service and the World Health Organization (WHO)-accredited regional reference polio laboratory. All cases of AFP reported to the Disease Surveillance Network from all six zones during this period were included in the study. In total, 5111 cases of AFP in children aged ≤15 years were reported between 2011 and 2014. These cases were investigated and verified by WHO surveillance officers using a standard questionnaire, which captured the number of doses of oral polio vaccine (OPV) received by the child. Two stool samples were collected for each case, 24-48 h apart, within 14 days of the onset of paralysis, and transported to the national polio laboratory under reverse cold chain storage. Data retrieved were stored in an AFP database hosted by the WHO server. EPIINFO software was used to query the database and extract the information required for analysis in this study. The percentage of children who had received at least three doses of OPV (which serves as a threshold to measure immunity status) decreased from 87% in 2011 to 82% in 2014. The percentage of children who had not received any doses of OPV decreased from 2% in 2011 to 1% in 2014. Forty-eight percent of the children who had not received any doses of OPV were aged <1 year. Given the decrease in OPV immunity status, the region risks re-introduction of poliovirus. Swift steps should be taken to improve the immunization coverage, which would boost immunity status in Nigeria.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 058634110

Download citation: RISBibTeXText

PMID: 27302057

DOI: 10.1016/j.puhe.2016.05.009


Related references

Viral Aetiology of Acute Flaccid Paralysis Surveillance Cases, before and after Vaccine Policy Change from Oral Polio Vaccine to Inactivated Polio Vaccine. Journal of Tropical Medicine 2014: 814908, 2014

The global switch from trivalent oral polio vaccine (tOPV) to bivalent oral polio vaccine (bOPV): facts, experiences and lessons learned from the south-south zone; Nigeria, April 2016. Bmc Infectious Diseases 18(1): 57, 2018

Non-polio enteroviruses in acute flaccid paralysis children of India: vital assessment before polio eradication. Journal of Paediatrics and Child Health 45(7-8): 409-413, 2009

Identification of non polio enteroviruses isolated from selected acute flaccid paralysis (AFP) stool samples in the Ghana polio regional reference laboratory: Implication for causative agents to AFP other than polio. 2007

Non-polio enteroviruses in faeces of children diagnosed with acute flaccid paralysis in Nigeria. Virology Journal 14(1): 175, 2017

Knowledge assessment regarding poliomyelitis among the caregivers of children who received oral polio vaccine reveals lack of awareness of the vaccine vial monitor (VVM): Implications extending beyond polio eradication. Tropical Doctor 47(3): 239-242, 2017

Strengthening the Acute Flaccid Paralysis (AFP) Surveillance Component of the Polio Eradication Initiative through Short Message Service (SMS) Reminders; Experience from Sokoto State, Nigeria 2014. Journal of Immunological Sciences Suppl(10): 68-74, 2018

Characterization of the non-polio enterovirus infections associated with acute flaccid paralysis in South-Western India. Plos one 8(4): E61650, 2013

Correlation between Non-Polio Acute Flaccid Paralysis Rates with Pulse Polio Frequency in India. International Journal of Environmental Research and Public Health 15(8):, 2018

Serum IgG and IgA levels in polio and non-polio acute flaccid paralysis cases in western Uttar Pradesh, India. Indian Pediatrics 52(3): 220-222, 2015

Role of Serial Polio Seroprevalence Studies in Guiding Implementation of the Polio Eradication Initiative in Kano, Nigeria: 2011-2014. Journal of Infectious Diseases 213(Suppl. 3): S124-S130, 2016

Characterization of group B coxsackieviruses isolated from non-polio acute flaccid paralysis patients in Pakistan: vital assessment before polio eradication. Epidemiology and Infection 145(12): 2473-2481, 2017

May a breast feeding mother receive oral polio (Sabin) vaccine, even if the baby is less than 3 months old and therefore has not received oral polio vaccine?. Monatsschrift Kinderheilkunde 141(8): 674, 1993

Risk of polio reintroduction to border regions of Islamic Republic of Iran: seroprevalence study of children with at least 5 doses of oral polio vaccine. Eastern Mediterranean Health Journal 20(5): 287-294, 2014

Intestinal Immunity to Poliovirus Following Sequential Trivalent Inactivated Polio Vaccine/Bivalent Oral Polio Vaccine and Trivalent Inactivated Polio Vaccine-only Immunization Schedules: Analysis of an Open-label, Randomized, Controlled Trial in Chilean Infants. Clinical Infectious Diseases 67(Suppl_1): S42-S50, 2018