+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Recent Advances of Natural and Synthetic β-Carbolines as Anticancer Agents



Recent Advances of Natural and Synthetic β-Carbolines as Anticancer Agents



Anti-Cancer Agents in Medicinal Chemistry 15(5): 537-547



Cancer is a leading cause of mortality worldwide, being responsible for millions of deaths annually. Therefore, novel cancer chemotherapeutic agents are urgently needed to combat this devastating disease. β - Carboline alkaloids are an important class of natural products and medicinal molecules, which exert their anticancer activities through diverse mechanisms. In this review, we cover recent natural and synthetic β - carbolines with anticancer activity that have been reported in the literature (2010-July 2014), focusing on their chemical structures, anticancer properties, structure-activity relationships, and mechanisms of action.

(PDF emailed within 1 workday: $29.90)

Accession: 058704954

Download citation: RISBibTeXText

PMID: 25430895


Related references

Synthetic advances in macrosphelides: natural anticancer agents. Molecules 19(10): 15982-16000, 2015

Recent advances in pharmacologic study of natural anticancer agents in China. Memorias do Instituto Oswaldo Cruz 86 Suppl 2: 51-54, 1991

Recent advances in synthetic lipopeptides as anti-microbial agents: designs and synthetic approaches. Amino Acids 49(10): 1653-1677, 2017

Overview: Recent Advances in Antifolates as Anticancer Agents. Expert Opinion on Therapeutic Patents 2(12): 1979-1992, 1992

Recent Advances in Development of Polyphenols as Anticancer Agents. Mini Reviews in Medicinal Chemistry 18(15): 1265-1269, 2018

Recent advances in the new generation taxane anticancer agents. Medicinal Chemistry ) 1(2): 125-139, 2006

Recent Advances in Copper Intercalators as Anticancer Agents. Journal of Fluorescence 28(5): 1195-1205, 2018

Novel anticancer agents and targets: recent advances and future perspectives. Mini Reviews in Medicinal Chemistry 13(9): 1239-1255, 2014

Recent advances in oral anticancer agents for colon cancer. Future Oncology 9(12): 1893-1908, 2014

Recent Advances in the Development of Indazole-based Anticancer Agents. Chemmedchem 13(15): 1490-1507, 2018

Transition Metal Intercalators as Anticancer Agents-Recent Advances. International Journal of Molecular Sciences 17(11), 2016

Natural and synthetic biologically active dimeric molecules: anticancer agents, anti-HIV agents, steroid derivatives and opioid antagonists. Current Medicinal Chemistry 13(2): 131-154, 2006

Recent advances in the development of thioredoxin reductase inhibitors as anticancer agents. Current Drug Targets 13(11): 1432-1444, 2013

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents. European Journal of Medicinal Chemistry 142: 459-485, 2017

Recent advances in multinuclear complexes as potential anticancer and DNA binding agents. Anti-Cancer Agents in Medicinal Chemistry 14(1): 147-169, 2014