+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Rehabilitation for Parkinson's disease: Current outlook and future challenges

Rehabilitation for Parkinson's disease: Current outlook and future challenges

Parkinsonism and Related Disorders 22(Suppl. 1): S60-S64

Rehabilitation is considered as an adjuvant to pharmacological and surgical treatments for Parkinson's disease (PD) to maximize functional ability and minimize secondary complications. Originally, approaches were based on empirical experience, but growing evidence suggests that exercise-dependent plasticity constitutes the main mechanism underlying the effects of physiotherapy. Exercise increases synaptic strength and influences neurotransmission, thus potentiating functional circuitry in PD. In addition, exercise is a pivotal element of motor learning. PD patients retain a sufficient capacity of motor learning, though learning rates and performance are reduced in comparison to normal controls. Recent meta-analyses demonstrated that rehabilitation could induce short-lasting, but clinically important benefits, particularly for gait and balance. However, the interventions are largely heterogeneous (stretching, muscle strengthening, balance, postural exercises, occupational therapy, cueing, treadmill training), and there is still no consensus about the optimal approach. Innovative techniques have been recently proposed: virtual reality and exergaming, motor imagery and action observation, robot-assisted physiotherapy and non-conventional therapies (e.g.: dance, martial arts). The rehabilitative program for PD should be "goal-based" (targeted to practicing and learning specific activities in the core areas), but a number of practice variables (intensity, specificity, complexity) need to be identified and the program should tailored to the individual patients' characteristics.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 058726703

Download citation: RISBibTeXText

PMID: 26360239

DOI: 10.1016/j.parkreldis.2015.09.005

Related references

Deep brain stimulation for Parkinson's disease: current status and future outlook. Neurodegenerative Disease Management 6(4): 299-317, 2017

Multidisciplinary rehabilitation in Parkinson's disease: A milestone with future challenges. Movement Disorders 30(8): 1011-1013, 2016

Parkinson's disease: Current and future challenges. Neurotoxicology (Little Rock) 23(4-5): 443-450, 2002

Tele-monitored tDCS rehabilitation: feasibility, challenges and future perspectives in Parkinson's disease. Journal of Neuroengineering and Rehabilitation 16(1): 20, 2019

Exosomes in Parkinson's disease: current perspectives and future challenges. Acs Chemical Neuroscience 2019, 2019

Disease Modification in Parkinson's Disease: Current Approaches, Challenges, and Future Considerations. Movement Disorders 33(5): 660-677, 2018

Inpatient management of Parkinson disease: current challenges and future directions. Neurohospitalist 2(1): 28-35, 2012

Retinal prostheses: current challenges and future outlook. Journal of Biomaterials Science. Polymer Edition 18(8): 1031-1055, 2007

Global poultry production: current state and future outlook and challenges. Worlds Poultry Science Journal 73(2): 245-256, 2017

Clinical utility of microarrays: current status, existing challenges and future outlook. Current Genomics 9(7): 466-474, 2009

Outpatient based colorectal cancer treatment--the current status, challenges and future outlook. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 33(5): 606-610, 2006

Current Strategies and Future Perspectives of Skin-on-a-Chip Platforms: Innovations, Technical Challenges and Commercial Outlook. Current Pharmaceutical Design 2019, 2019

Genotype Diversity of Newcastle Disease Virus in Nigeria: Disease Control Challenges and Future Outlook. Advances in Virology 2018: 6097291-6097291, 2019

Cardiac rehabilitation: current status and future challenges. Herz 37(1): 22-29, 2012

Interdisciplinary pain rehabilitation: current challenges and future opportunities. Pain Medicine 12(1): 152-153, 2011