Remineralizing potential of a 60-s in vitro application of Tooth Mousse Plus

Gopalakrishnan, V.L.; Anthonappa, R.P.; King, N.M.; Itthagarun, A.

International Journal of Paediatric Dentistry 27(5): 356-363

2017


ISSN/ISBN: 1365-263X
PMID: 27659165
DOI: 10.1111/ipd.12268
Accession: 058736148

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Abstract
No published studies exist on the remineralizing potential of Tooth Mousse Plus® (TMP) when applied for less than 3 min. To evaluate (i) the remineralizing potential of TMP on artificial carious lesions, when applied thrice daily for 60 s, and (ii) the benefit of using a fluoridated dentifrice prior to TMP application. Carious lesions, 120-200 μm deep, were produced by placing molars in demineralizing solution for 96 h, and sections 100-150 μm thick were then randomly assigned to four groups. Specimens were treated thrice daily with a non-fluoridated (Group A), or 1000 ppm F dentifrice (Group B), or TMP (Group C), or a 1000 ppm F dentifrice followed by TMP application (Group D), and then subjected to a 10-day pH cycling model. Lesion evaluation involved polarizing light microscopy and microradiography. Post-treatment maximum mineral content at the surface zone (Vmax ) was significantly increased and lesion depth (LD) significantly decreased in Group C, while only the Vmax increased in Group D. Increase in LD was observed in Group B; however, no significant differences were noted in percentage LD changes between groups B, C, and D (P > 0.05). TMP applied for 60 s significantly remineralized the artificial carious lesions. No additional benefit was evident when TMP was preceded by treatment with 1000 ppm F dentifrice.