+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Do Women and Men Have the Same Patterns of Multiple Occupational Carcinogenic Exposures? Results from a Cohort of Cancer Patients

Do Women and Men Have the Same Patterns of Multiple Occupational Carcinogenic Exposures? Results from a Cohort of Cancer Patients

Annals of Work Exposures and Health 62(4): 450-464

Complex exposure situations are frequent at the workplace, but few studies have characterized multiple occupational carcinogenic exposures (MOCE) and their gendered differences across jobs' characteristics. We assessed MOCE separately in male and female jobs and identified patterns of MOCE at job level. Participants (834 men and 183 women) were cancer patients recruited between March 2002 and December 2010 in the ongoing SCOP93 cohort study, Seine-Saint-Denis department, France. Job histories were collected through personal interviews, and carcinogenic exposures were assessed by a multidisciplinary expert committee using a list of 53 carcinogens. Proportion of MOCE (i.e. ≥2 carcinogens) was assessed for male and female jobs separately. Principal component analysis combined with hierarchical ascendant classification was used to identify patterns of MOCE. Among the 5202 male jobs and 885 female jobs, respectively 42 and 9% were multi-exposed. Blue-collar workers and jobs in the construction and industry sectors had the highest rates of MOCE, contrasting with jobs held in recent periods (≥1997) and by patients aged ≥45 years at job start. A gradient of MOCE was also observed according to occupational segregation for both men and women. Eight patterns of MOCE were identified among male jobs: widespread carcinogens, mixed silica dust, heavy metals/combustion products, organic compounds/radiation, metal working, solvents/heavy metals, wood dust/formaldehyde/pesticides, and fuel exhausts. Three patterns of MOCE were found among female jobs: biological/organic compounds, industrial working, and fuel exhausts. Some patterns of MOCE were job-specific, whereas other patterns were found across different occupations. These results suggest that patterns of MOCE partly differ between men and women. They stress the importance of gendering multiple exposure assessment studies and point out the inadequacy of occupational disease compensation systems based on a single factor and non-gendered approach of carcinogenesis, ignoring differences between men and women in complex occupational exposure situations.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 058768942

Download citation: RISBibTeXText

PMID: 29471379

DOI: 10.1093/annweh/wxx116

Related references

P6-2Gendered patterns of multiple occupational carcinogenic exposures. results at the job level from a cohort of patients with mostly respiratory cancer (seine-saint-denis, france). Occupational and Environmental Medicine 73(Suppl 1): A93.2-A94, 2016

Professional trajectory is associated with multiple carcinogenic exposures at work among men : data from a cohort of patients suffering respiratory cancer. Occupational and Environmental Medicine 71(Suppl_1): A85-A86, 2014

Lung cancer risk and occupational exposures in crop farming: results from the AGRIculture and CANcer (AGRICAN) cohort. Occupational and Environmental Medicine 75(11): 776-785, 2018

Risks of biliary tract cancer and occupational exposures among Shanghai women textile workers: a case-cohort study. American Journal of Industrial Medicine 49(8): 690-698, 2006

Systematic Screening for Occupational Exposures in Lung Cancer Patients: A Prospective French Cohort. International Journal of Environmental Research and Public Health 15(1):, 2018

Propoumon: Systematic screening for occupational exposures in lung cancer patients. A prospective French cohort. Revue d'Épidémiologie et de Santé Publique 66: S246-S247, 2018

Occupational exposures and sick leave during pregnancy: results from a Danish cohort study. Scandinavian Journal of Work Environment and Health 41(4): 397-406, 2015

Iarc international agency for research on cancer monographs on the evaluation of carcinogenic risks to humans vol 53 occupational exposures in insecticide application and some pesticides. International Agency For Research On Cancer. Iarc (international Agency For Research On Cancer) Monographs On The Evaluation Of Carcinogenic Risks To Humans, Vol. 53. Occupational Exposures In Insecticide Application, And Some Pesticides. 612p. International Agency For Research On Cancer: Lyon, France. Illus. Paper. 612p, 1991

The occupational role of women in military service: validation of occupation and prevalence of exposures in the Millennium Cohort Study. International Journal of Environmental Health Research 17(4): 271-284, 2007

Multiple sclerosis and occupational exposures: results of an explorative study. Giornale Italiano di Medicina del Lavoro Ed Ergonomia 35(3): 133-137, 2014

A case-referent study of lung cancer, occupational exposures and smoking. III. Etiologic fraction of occupational exposures. Scandinavian Journal of Work Environment and Health 12(3): 210-215, 1986

Occupational exposures and ovarian cancer: A national population-based cohort study. Gynecologic Oncology 130(1): E142-E143, 2013

Breast cancer and occupational exposures in women in Finland. American Journal of Industrial Medicine 36(1): 48-53, 1999

Environmental and occupational exposures in relation to cancer among women. AAAS Annual Meeting & Science Innovation Exposition 168: A4-A5, 14-19 February, 2002

Non-Hodgkin lymphoma and occupational exposures: multiple exposures not = multiple papers. Occupational and Environmental Medicine 64(1): 4-5, 2007