+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Risk Factors and Age-Related Macular Degeneration in a Mediterranean-Basin Population: The PAMDI (Prevalence of Age-Related Macular Degeneration in Italy) Study--Report 2



Risk Factors and Age-Related Macular Degeneration in a Mediterranean-Basin Population: The PAMDI (Prevalence of Age-Related Macular Degeneration in Italy) Study--Report 2



Ophthalmic Research 55(3): 111-118



To investigate the association of diet and other modifiable risk factors with the prevalence of age-related macular degeneration (ARMD) in rural and urban communities of a Mediterranean population in the northeast of Italy. A cross-sectional population-based study was conducted among subjects aged over 60 years. A food frequency questionnaire (FFQ) was used to assess the consumption of different food categories, i.e., protective (P), risky (R), lutein-rich (L) and neutral (N). Smoking habit and alcohol intake were also examined. Macular pigment was measured by Raman spectroscopy. P food intake reduced the risk of large drusen (ARM2; OR 0.93; 95% CI 0.89-0.96) within the rural community. In this sub-group, R foods resulted in a slight association with large drusen, though the R/P food ratio was highly correlated with ARM2 (OR 1.21; 95% CI 1.12-1.31). Raman measures showed an age-dependent decrease but did not correlate with lutein intake. Smoking habit showed a positive association with ARM2 among women (OR 2.40; 95% CI 1.54-3.75), whereas alcohol consumption resulted in protective odds (OR 0.72; 95% CI 0.60-0.86). FFQ analysis confirmed the role of P and R foods and the benefit of a Mediterranean diet in ARMD. Moderate alcohol consumption showed a beneficial effect, whereas the deleterious role of a smoking habit was more evident in females.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 058776297

Download citation: RISBibTeXText

PMID: 26666641

DOI: 10.1159/000441795


Related references

The prevalence of age-related macular degeneration in Italy (PAMDI) study: report 1. Ophthalmic Epidemiology 18(3): 129-136, 2011

Prevalence and risk factors of age-related macular degeneration (AMD) in a Tunisian hospital population. Bulletin de la Societe Belge d'Ophtalmologie 2012(319): 35-41, 2012

Association of Hyperreflective Foci Present in Early Forms of Age-Related Macular Degeneration With Known Age-Related Macular Degeneration Risk Polymorphisms. Investigative Ophthalmology and Visual Science 57(10): 4315-4320, 2016

Age-related macular degeneration in a screened South Korean population: prevalence, risk factors, and subtypes. Ophthalmic Epidemiology 16(5): 304-310, 2009

Prevalence and risk factors for age-related macular degeneration in an adult Japanese population: the Funagata study. Ophthalmology 115(8): 1376-81, 1381.E1-2, 2008

Prevalence and risk factors for age related macular degeneration in a population based sample of us hispanics proyecto ver. ARVO Annual Meeting Abstract Search & Program Planner : Abstract No 3154, 2003

Prevalence and associated risk factors of age-related macular degeneration in an elderly Chinese population in Taiwan: the Shihpai Eye Study. Investigative Ophthalmology and Visual Science 49(7): 3126-3133, 2008

Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population. British Journal of Ophthalmology 102(12): 1691-1695, 2018

Age-related macular degeneration in Portugal: prevalence and risk factors in a coastal and an inland town. The Coimbra Eye Study - Report 2. Acta Ophthalmologica 94(6): E442-E453, 2016

The prevalence of age-related macular degeneration and associated risk factors. Archives of Ophthalmology 128(6): 750-758, 2010

Macular function in eyes with early age-related macular degeneration with or without contralateral late age-related macular degeneration. Retina 27(7): 879-890, 2007

Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population. Investigative Ophthalmology & Visual Science 42(2): 439-446, 2001

Bilateral macular drusen in age-related macular degeneration. Prognosis and risk factors. Ophthalmology 101(9): 1522-1528, 1994

Development of typical age-related macular degeneration and polypoidal choroidal vasculopathy in fellow eyes of Japanese patients with exudative age-related macular degeneration. American Journal of Ophthalmology 146(1): 96, 2008

Visual acuity and contrast sensitivity in patients with neovascular age-related macular degeneration. Results from the Radiation Therapy for Age-Related Macular Degeneration (RAD-) Study. Graefe's Archive for Clinical and Experimental Ophthalmology 241(12): 968-974, 2003