+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Risk of self-harm and nonfatal suicide attempts, and completed suicide in patients with psoriasis: a population-based cohort study

Risk of self-harm and nonfatal suicide attempts, and completed suicide in patients with psoriasis: a population-based cohort study

British Journal of Dermatology 175(3): 493-500

Psoriasis is a common inflammatory skin disease, and inflammation may affect suicidal behaviour. Current data on the incidence and risk of suicidal behaviour in patients with psoriasis are scarce. We investigated the association between psoriasis and the risk of self-harm and suicide attempts and suicides. All Danish patients aged ≥ 18 years with mild or severe psoriasis (cases) from 1 January 1997 to 31 December 2011 were matched on age, sex and calendar time 1 : 5 with healthy controls. The outcome was a diagnosis of self-harm or a nonfatal suicide attempt, or completed suicide. Incidence rates per 10 000 person-years were calculated, and incidence rate ratios (IRRs) and confidence intervals (CIs) were estimated by Poisson regression models. The study cohort comprised 408 663 individuals, including 57 502 and 11 009 patients with mild and severe psoriasis, respectively. In total 280 cases of self-harm or suicide attempts, and 574 suicides occurred during follow-up. There was no increased risk of self-harm or suicide attempts in patients with mild psoriasis (IRR 1·01, 95% CI 0·17-2·01), but this risk was significantly increased in severe psoriasis (IRR 1·69, 95% CI 1·00-2·84). There was no increased risk of suicides in mild (IRR 1·05, 95% CI 0·84-1·32) or severe psoriasis (IRR 0·78, 95% CI 0·45-1·36). Similar results were found when suicides were confirmed by official forensic investigations, and when psoriasis was compared with atopic dermatitis. We found limited evidence to suggest an increased risk of self-harm and nonfatal suicide attempts in patients with psoriasis. Importantly, after adjustment for psoriatic arthritis this risk was no longer significantly increased. The risk of completed suicide was also not increased, regardless of psoriasis severity.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 058781036

Download citation: RISBibTeXText

PMID: 27038335

DOI: 10.1111/bjd.14633

Related references

Childhood bullying behaviors as a risk for suicide attempts and completed suicides: a population-based birth cohort study. Journal of the American Academy of Child and Adolescent Psychiatry 48(3): 254-261, 2009

Antidepressants increase risk of suicide attempt, but not completed suicide, in people with previous suicide attempts. Evidence-BasedMentalHealth10(3):90, 2007

Suicide risk assessment: a review of risk factors for suicide in 100 patients who made severe suicide attempts. Evaluation of suicide risk in a time of managed care. Psychosomatics 40(1): 18-27, 1999

Switching suicide methods as a predictor of completed suicide in individuals with repeated self-harm: a community cohort study in northern Taiwan. Australian and new Zealand Journal of Psychiatry 49(1): 65-73, 2015

Risk of suicide attempts among colorectal cancer patients: A nationwide population-based matched cohort study. Psycho-Oncology 27(12): 2794-2801, 2018

The relationship of nonfatal suicide attempts to completed suicides. Maris, R W , Et Al (Ed ) Assessment And Prediction Of Suicide Xxii+697p Guilford Press: New York, New York, Usa; London, England, Uk Illus 362-380, 1992

Suicide risk after nonfatal self-harm: a national cohort study, 2000-2008. Journal of Clinical Psychiatry 77(2): 240-246, 2016

Completed suicide and suicide attempts in the Arab population in Israel. Social Psychiatry and Psychiatric Epidemiology 51(6): 869-876, 2016

Suicide and suicide attempts in people with severe mental disorders in Butajira, Ethiopia: 10 year follow-up of a population-based cohort. Bmc Psychiatry 14: 150, 2014

Completed suicide after attempted suicide: Methods used in attempts may indicate the degree of risk. BMJ 341(7765): 158-159, 2010

Are previous suicide attempts a risk factor for completed suicide?. Psicothema 30(1): 33-38, 2018

Sex difference in risk period for completed suicide following prior attempts: Korea National Suicide Survey (KNSS). Journal of Affective Disorders 227: 861-868, 2018

The Longitudinal Association of Being Bullied and Gender with Suicide Ideations, Self-Harm, and Suicide Attempts from Adolescence to Young Adulthood: A Cohort Study. Suicide and Life-Threatening Behavior 48(2): 169-182, 2018

Suicide Ideations, Suicide Attempts, and Completed Suicide in Persons with Pathological Gambling and Their First-Degree Relatives. Suicide and Life-Threatening Behavior 45(6): 700-709, 2015

Risk of suicide and suicide attempts associated with physical disorders: a population-based, balancing score-matched analysis. Psychological Medicine 45(3): 495-504, 2015