+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Specular microscopy to determine corneal endothelial cell morphology and morphometry in chinchillas (Chinchilla lanigera) in vivo

Specular microscopy to determine corneal endothelial cell morphology and morphometry in chinchillas (Chinchilla lanigera) in vivo

Veterinary Ophthalmology 18(Suppl. 1): 137-142

The purpose of this study was to measure cell density, average area, and morphology of corneal endothelium of chinchillas in different age groups. The corneal endothelium was studied with a contact specular microscope. Thirty chinchillas (Chinchilla lanigera) were evaluated, and 30 male chinchillas were divided into three groups of 10 chinchillas each, by age: Group 1 (2-4-month-old), Group 2 (48-month-old), and Group 3 (10 years of age). Data are presented as endothelial cell density (ECD), average cell area, and pleomorphism. Endothelial cell density decreases and an increase in endothelial cell area and pleomorphism were observed with age, in the corneas of normal chinchillas. For Group 1 chinchillas, the mean cell density was 3.423 cells per mm(2) . The mean ECD for Group 2 chinchillas was 2.650 cells per mm(2) . The mean ECD for Group 3 chinchillas was 2.124 cells per mm(2) . The average area for Group 1 chinchillas was 350.5 μm(2) . The average area for Group 2 chinchillas was 442.15 μm(2) . The average area for Group 3 chinchillas was 583.64 μm(2) . The pleomorphism for Group 1 was 70.05%. The pleomorphism for Group 2 was 65.18%, and the pleomorphism for Group 3 was 62.28%. The results suggested that chinchilla corneal endothelium undergoes age-related changes. Moreover, with advancing age, the mean cell area increased and cell density decreased.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 058887866

Download citation: RISBibTeXText

PMID: 25469785

DOI: 10.1111/vop.12236

Related references

Use of specular microscopy to determine corneal endothelial cell morphology and morphometry in enucleated cat eyes. Veterinary Ophthalmology 13(4): 222-226, 2010

Comparison between laser scanning in vivo confocal microscopy and noncontact specular microscopy in assessing corneal endothelial cell density and central corneal thickness. Cornea 30(7): 754-759, 2011

Assessment of central corneal thickness and corneal endothelial morphology using ultrasound pachymetry, non-contact specular microscopy, and Confoscan 4 confocal microscopy. Bmc Ophthalmology 13: 73, 2014

A prospective analysis of donor corneal endothelial cell counts and morphology by video specular microscopy. Investigative Ophthalmology & Visual Science 35(4): 1880, 1994

Comparison of protozoan infection between chinchillas chinchilla lanigera from a commercial breeding facility in southern brazil and chinchillas from a natural reserve in chile. 2012

Megaesophagus in a chinchilla Chinchilla lanigera A case report Megaoesophagus bei einem Chinchilla Chinchilla lanigera Ein Fallbericht. Tieraerztliche Praxis Ausgabe K Kleintiere Heimtiere, 322: 96-100, 2004

Donor age and corneal endothelial cell loss 5 years after successful corneal transplantation. Specular microscopy ancillary study results. Ophthalmology 115(4): 627-632.E8, 2008

Heatstroke in chinchillas (Chinchilla lanigera). 1977

Urinalysis in chinchillas (Chinchilla lanigera). Journal of the American Veterinary Medical Association 248(8): 901-907, 2016

Endothelial cell density and characterization of corneal endothelial cells in the Tawny Owl (Strix aluco) using specular microscopy. Veterinary Ophthalmology 2018, 2018

Ophthalmic Disorders Observed in Pet Chinchillas (Chinchilla lanigera). Journal of Exotic Pet Medicine 23(2): 201-205, 2014

Neurological examination in healthy chinchillas ( Chinchilla lanigera). Laboratory Animals 51(6): 629-635, 2018

Ethological examination of breeding chinchillas (Chinchilla lanigera). Scientifur 20(1): 35-41, 1996

Vertebral heart size in chinchillas (Chinchilla lanigera) usingradiography and CT. Journal of Small Animal Practice 58(12): 714-719, 2017

Analgesic Efficacy and Safety of Buprenorphine in Chinchillas ( Chinchilla lanigera ). Journal of the American Association for Laboratory Animal Science 57(3): 286-290, 2018