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Sphenoid sinus aspergilloma in trans-sphenoidal surgery for pituitary adenomas



Sphenoid sinus aspergilloma in trans-sphenoidal surgery for pituitary adenomas



Acta Neurochirurgica 157(8): 1345



Simultaneous appearance of sphenoid sinus aspergilloma and pituitary adenoma is a very rare finding. Retrospective analysis of patients with sellar and sphenoid sinus mass lesions who underwent trans-sphenoidal surgery was performed. Demographic data, medical history, predisposing factors, clinical picture, neurological status and radiological findings were reviewed. All patients underwent a trans-sphenoidal microsurgical treatment, and acquired specimens underwent both histopathological and microbiological analysis. Sphenoid sinus aspergilloma was encountered in seven patients. Three patients had an isolated sphenoid sinus aspergilloma and four patients with pituitary macroadenoma had a sphenoid aspergilloma as an incidental finding. Sphenoid sinus aspergilloma can be found during trans-sphenoidal surgery for pituitary adenomas. Sphenoid sinus extirpation followed by adenomectomy is the treatment of choice unless invasive aspergilloma is encountered requiring additional antifungal therapy.

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Accession: 058888570

Download citation: RISBibTeXText

PMID: 26126762

DOI: 10.1007/s00701-015-2485-6


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