EurekaMag
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Starvation beneficially influences the liver physiology and nutrient metabolism in Edwardsiella tarda infected red sea bream (Pagrus major)


Starvation beneficially influences the liver physiology and nutrient metabolism in Edwardsiella tarda infected red sea bream (Pagrus major)



Comparative Biochemistry and Physiology. Part A Molecular and Integrative Physiology 189: 1-10



ISSN/ISBN: 1095-6433

PMID: 26188170

DOI: 10.1016/j.cbpa.2015.07.003

Dietary compromises, especially food restrictions, possess species-specific effects on the health status and infection control in several organisms, including fish. To understand the starvation-mediated physiological responses in Edwardsiella tarda infected red sea bream, especially in the liver, we performed a 20-day starvation experiment using 4 treatment (2 fed and 2 starved) groups, namely, fed-placebo, starved-placebo, fed-infected, and starved-infected, wherein bacterial exposure was done on the 11th day. In the present study, the starved groups showed reduced hepatosomatic index and drastic depletion in glycogen storage and vacuole formation. The fed-infected fish showed significant (P<0.05) increase in catalase and superoxide dismutase activity in relation to its starved equivalent. Significant (P<0.05) alteration in glucose and energy metabolism, as evident from hexokinase and glucose-6-phosphate dehydrogenase activity, was recorded in the starved groups. Interestingly, coinciding with the liver histology, PPAR (peroxisome proliferator activated receptors) α transcription followed a time-dependent activation in starved groups while PPARγ exhibited an opposite pattern. The transcription of hepcidin 1 and transferrin, initially increased in 0dai (days after infection) starved fish but reduced significantly (P<0.05) at later stages. Two-color immunohistochemistry and subsequent cell counting showed significant increase in P63-positive cells at 0dai and 5dai but later reduced slightly at 10dai. Similar results were also obtained in the lysosomal (cathepsin D) and non-lysosomal (ubiquitin) gene transcription level. All together, our data suggest that starvation exerts multidirectional responses, which allows for better physiological adaptations during any infectious period, in red sea bream.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 058899362

Download citation: RISBibTeXText

Related references

Short-term starvation and realimentation helps stave off Edwardsiella tarda infection in red sea bream (Pagrus major). Comparative Biochemistry and Physiology. Part B Biochemistry and Molecular Biology 206: 42-53, 2017

Molecular cloning, characterization and expression analysis of complement components in red sea bream (Pagrus major) after Edwardsiella tarda and red sea bream Iridovirus (RSIV) challenge. Fish and Shellfish Immunology 82: 286-295, 2018

Effect of hypoxic stress on energy metabolism in Red Sea bream, Pagrus major - II. Response of enzyme activities and metabolite concentrations in various tissues of Red Sea bream, Pagrus major, subjected to hypoxic exposure. Suisan Zoshoku 50(3): 325-331, 2002

Carrying situation in red sea bream artificially infected with Edwardsiella tarda. Nippon Suisan Gakkaishi 80(4): 572-577, 2014

Metabolism of 2-nitrofluorene, an environmental pollutant, by liver preparations of sea bream, Pagrus major. Xenobiotica; the Fate of Foreign Compounds in Biological Systems 32(8): 667-682, 2002

Effect of hypoxic stress on energy metabolism in Red Sea bream, Pagrus major - I. Stress response and energy status in various tissues of Red Sea bream, Pagrus major, subjected to hypoxic exposure. Suisan Zoshoku 50(3): 315-323, 2002

Effect of dietary vitamins C and E fortification on lipid metabolism in red sea bream Pagrus major and black sea bream Acanthopagrus schlegeli. Fisheries Science Tokyo ober; 69(5): 1001-1009, 2003

Effects of dietary tert-butylhydroquinone on domoic acid metabolism and transcription of detoxification-related liver genes in red sea bream Pagrus major. Chinese Science Bulletin 58(16): 1906-1911, 2013

Draft Genome Sequences of Two Genetic Variant Strains of Edwardsiella piscicida, JF1305 and RSB1309, Isolated from Olive Flounder (Paralichythys olivaceus) and Red Sea Bream (Pagrus major) Cultured in Japan, Respectively. Genome Announcements 2(3), 2014

Gonadal maturation of Pagrus major x Acanthopagrus schlegeli and Pagrus major x Sparus sarba sea bream hybrids. Suisan Zoshoku ch; 45(1): 75-80, 1997

Photoperiod influences the growth, food intake, feed efficiency and digestibility of red sea bream (Pagrus major). Aquaculture 250(3/4): 666-673, 2005

Dietary nucleotide administration influences growth, immune responses and oxidative stress resistance of juvenile red sea bream (Pagrus major). Aquaculture 455: 41-49, 2016

Effect of supplemental carnitine on body weight loss, proximate and lipid compositions and carnitine content of red sea bream (Pagrus major) during starvation. Aquaculture 158(1/2): 129-140, 1997

Molecular Identification and mRNA Expression Profiles of Galectin-9 Gene in Red Sea Bream ( Pagrus major ) Infected with Pathogens. Animals: An Open Access Journal from Mdpi 11(1), 2021

Abundant and constant expression of uncoupling protein 2 in the liver of red sea bream Pagrus major. Comparative Biochemistry and Physiology. Part A Molecular and Integrative Physiology 136(3): 655-661, 2003