+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Dual respiratory and cardiac motion estimation in PET imaging: Methods design and quantitative evaluation

Dual respiratory and cardiac motion estimation in PET imaging: Methods design and quantitative evaluation

Medical Physics 45(4): 1481-1490

The goal of this study was to develop and evaluate four post-reconstruction respiratory and cardiac (R&C) motion vector field (MVF) estimation methods for cardiac 4D PET data. In Method 1, the dual R&C motions were estimated directly from the dual R&C gated images. In Method 2, respiratory motion (RM) and cardiac motion (CM) were separately estimated from the respiratory gated only and cardiac gated only images. The effects of RM on CM estimation were modeled in Method 3 by applying an image-based RM correction on the cardiac gated images before CM estimation, the effects of CM on RM estimation were neglected. Method 4 iteratively models the mutual effects of RM and CM during dual R&C motion estimations. Realistic simulation data were generated for quantitative evaluation of four methods. Almost noise-free PET projection data were generated from the 4D XCAT phantom with realistic R&C MVF using Monte Carlo simulation. Poisson noise was added to the scaled projection data to generate additional datasets of two more different noise levels. All the projection data were reconstructed using a 4D image reconstruction method to obtain dual R&C gated images. The four dual R&C MVF estimation methods were applied to the dual R&C gated images and the accuracy of motion estimation was quantitatively evaluated using the root mean square error (RMSE) of the estimated MVFs. Results show that among the four estimation methods, Methods 2 performed the worst for noise-free case while Method 1 performed the worst for noisy cases in terms of quantitative accuracy of the estimated MVF. Methods 4 and 3 showed comparable results and achieved RMSE lower by up to 35% than that in Method 1 for noisy cases. In conclusion, we have developed and evaluated 4 different post-reconstruction R&C MVF estimation methods for use in 4D PET imaging. Comparison of the performance of four methods on simulated data indicates separate R&C estimation with modeling of RM before CM estimation (Method 3) to be the best option for accurate estimation of dual R&C motion in clinical situation.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 058992200

Download citation: RISBibTeXText

PMID: 29405313

DOI: 10.1002/mp.12793

Related references

Evaluation of respiratory and cardiac motion correction schemes in dual gated PET/CT cardiac imaging. Medical Physics 41(7): 072504, 2015

Non-rigid dual respiratory and cardiac motion correction methods after, during, and before image reconstruction for 4D cardiac PET. Physics in Medicine and Biology 61(1): 151-168, 2016

Evaluation of motion-correction methods for dual-gated cardiac positron emission tomography/computed tomography imaging. Nuclear Medicine Communications 37(9): 956-968, 2017

Respiratory and cardiac motion correction in dual gated PET/MR imaging. Ejnmmi Physics 2(Suppl 1): A43, 2016

A quantitative study of motion estimation methods on 4D cardiac gated SPECT reconstruction. Medical Physics 39(8): 5182-5193, 2012

Quantitative Study of Rigid-Body and Respiratory Motion of Patients Undergoing Stress and Rest Cardiac SPECT Imaging. IEEE Transactions on Nuclear Science 57(3): 1105-1115, 2010

Joint cardiac and respiratory motion estimation for motion-corrected cardiac PET-MR. Physics in Medicine and Biology 64(1): 015007-015007, 2018

An evaluation of data-driven motion estimation in comparison to the usage of external-surrogates in cardiac SPECT imaging. Physics in Medicine and Biology 58(21): 7625-7646, 2014

Comparison of the Diagnostic Performance of Four Quantitative Myocardial Perfusion Estimation Methods Used in Cardiac MR Imaging: CE-MARC Substudy. Radiology 275(2): 393-402, 2015

A Quantitative Study of the Correlations of Lung Tumor Motion to Cardiac and Respiratory Motion. International Journal of Radiation Oncology*biology*physics 84(3): S742-S743, 2012

A dual-chamber, thick-walled cardiac phantom for use in cardiac motion and deformation imaging by ultrasound. Ultrasound in Medicine and Biology 36(7): 1145-1156, 2010

Evaluation of a direct motion estimation/correction method in respiratory-gated PET/MRI with motion-adjusted attenuation. Medical Physics 44(6): 2379-2390, 2017

Estimation of cardiac event risk by gated myocardial perfusion imaging and quantitative scoring methods based on a multi-center J-ACCESS database. Circulation Journal 75(10): 2417-2423, 2012

Estimation of Cardiac Respiratory-Motion by Semi-Automatic Segmentation and Registration of Non-Contrast-Enhanced 4D-CT Cardiac Datasets. IEEE Transactions on Nuclear Science 56(6): 3662-3671, 2010

Cardiac MR imaging with external respirator: synchronizing cardiac and respiratory motion--feasibility study. Radiology 227(3): 877-882, 2003