+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Ultrasonic characteristics of thyroid nodules and diagnostic value of Thyroid Imaging Reporting and Data System (TI-RADS) in the ultrosound evaluation of thyroid nodules



Ultrasonic characteristics of thyroid nodules and diagnostic value of Thyroid Imaging Reporting and Data System (TI-RADS) in the ultrosound evaluation of thyroid nodules



Zhonghua Zhong Liu Za Zhi 37(2): 138-142



To seek for the ultrasound findings of thyroid nodules related to malignancy and benign, and to assess the role of TI-RADS in the ultrosound evaluation of thyroid nodules. We reviewed and analyzed the ultrasound characteristics of 1838 thyroid nodules confirmed by biopsy or surgical pathology, classified the thyroid nodules by TI-RADS grading criteria, and analyzed the malignancy rate and accuracy rate of different TI-RADS grading. Among the 1 838 thyroid nodules, 1 160 cases were carcinomas confirmed by surgery, while benign nodules in 212 cases. The sensitivity, specificity, PPV, NPV, and accuracy rates were 99.7% (1 156/1 160), 41.0%(278/678), 74.3% (1 156/1 556), 98.6% (278/282), and 78.2% (1 434/1 838), respectively. There were significant differences between the malignant and benign thyroid nodules in echo, margin, shape, calcification, and blood flow (P<0.001). Hypoechogenicity, marked hypoechogenicity, ill-defined margin, microcalcification, a taller-than-wide shape, and nodule internal rich flow (type III) were significantly associated with malignancy, while hyper/isoechogenicity, smooth margin, macro/no-calcifications, a wider-than-tall shape, and nodules internal poor flow (type I or type II) were significantly associated with benign nodules. There were significant differences between the malignant rates and accuracy rates obtained by different TI-RADS classifications (P<0.01). Understanding the ultrasound characteristics of benign and malignant thyroid nodules and applying TI-RADS grading criteria to correctly classify the thyroid nodules are crucial for the clinical treatment and prognosis.

(PDF emailed within 1 workday: $29.90)

Accession: 059190764

Download citation: RISBibTeXText

PMID: 25975692


Related references

Thyroid imaging reporting and data system (TI-RADS) in the diagnostic value of thyroid nodules: a systematic review. Tumour Biology 35(7): 6769-6776, 2014

Diagnostic performance of thyroid imaging reporting and data system (TI-RADS) alone and in combination with contrast-enhanced ultrasonography for the characterization of thyroid nodules. Clinical Hemorheology and Microcirculation 2018, 2018

Use of the thyroid imaging, reporting, and data system (TI-RADS) scoring system for the evaluation of subcentimeter thyroid nodules. Cancer Cytopathology 126(8): 518-524, 2018

Characterization of thyroid nodules using the proposed thyroid imaging reporting and data system (TI-RADS). Head and Neck 35(4): 541-547, 2013

Prospective validation of an ultrasound-based thyroid imaging reporting and data system (TI-RADS) on 3980 thyroid nodules. International Journal of Clinical and Experimental Medicine 8(4): 5911-5917, 2015

Likelihood of malignancy in thyroid nodules according to a proposed Thyroid Imaging Reporting and Data System (TI-RADS) classification merging suspicious and benign ultrasound features. Archives of Endocrinology and Metabolism 61(3): 211-221, 2017

Malignancy Risk Stratification of Thyroid Nodules: Comparison between the Thyroid Imaging Reporting and Data System and the 2014 American Thyroid Association Management Guidelines. Radiology 278(3): 917-924, 2016

Risk stratification of thyroid nodules using Thyroid Imaging Reporting And Data System (TIRADS): The omission of thyroid scintigraphy increases the rate of falsely suspected lesions. Journal of Nuclear Medicine 2018, 2018

Correlation of Thyroid Imaging Reporting and Data System [TI-RADS] and fine needle aspiration: experience in 1,000 nodules. Einstein 14(2): 119-123, 2017

Diagnosis value of thyroid imaging reporting and data system in thyroid nodules. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 29(14): 1264-1267, 2016

Meta-analysis of thyroid imaging reporting and data system in the ultrasonographic diagnosis of 10,437 thyroid nodules. Head and Neck 38(2): 309-315, 2016

Thyroid imaging reporting and data system in assessment of cytological Bethesda Category III thyroid nodules. Clinical Hemorheology and Microcirculation 65(2): 163-173, 2016

Application of Thyroid Imaging Reporting and Data System in the Ultrasound Assessment of Thyroid Nodules According to Physician Experience. Ultrasound Quarterly 32(2): 126-131, 2017

Interobserver agreement of Thyroid Imaging Reporting and Data System (TIRADS) and strain elastography for the assessment of thyroid nodules. Plos One 8(10): E77927, 2014

Malignancy risk of initially benign thyroid nodules: validation with various Thyroid Imaging Reporting and Data System guidelines. European Radiology 2018, 2018