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Analysis of Postoperative Complications and Risk Factors of Patients with Lung Cancer through Clavien-Dindo Classification

Analysis of Postoperative Complications and Risk Factors of Patients with Lung Cancer through Clavien-Dindo Classification

Zhongguo Fei Ai Za Zhi 20(4): 264-271

背景与目的 术后并发症是肺切除术后患者死亡的重要原因。在本研究中,我们应用Clavien-Dindo并发症分级系统对肺癌术后并发症按照严重程度进行分级,并分析术后并发症的发生率,探讨不同分级术后并发症的危险因素。方法 回顾性分析2013年6月-2014年12月四川大学华西医院胸外科966例行肺叶切除术的肺癌患者,依据术后30 d内是否发生并发症将此966例患者分为并发症组与无并发症组;同时根据Clavien-Dindo分级系统将并发症分为4级,并针对不同分级的并发症进行危险因素分析。结果 966例患者中,并发症组占15.0%(145/966),发生总数380次;依据Clavien-Dindo分级系统将此380次并发症进行分级,其中I级、II级、III级、IV级及以上分别占6.8%、75.3%、15.0%和2.9%。Logistic回归分析结果显示术前第1秒用力呼气容积(forded expiratory volume in one second, FEV1)、肺一氧化碳弥散量(diffusion capacity for carbon monoxide of the lung single breath, DLco SB)及术前合并慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)是术后并发症的独立危险因素;其中术前FEV1是I级、II级、III级及以上并发症的独立危险因素。结论 在Clavien-Dindo分级系统下,II级并发症在术后30天内最常见;FEV1与术后并发症的发生密切相关,可作为评估术后并发症发生风险的可靠指标之一。.

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Accession: 059354519

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PMID: 28442016

DOI: 10.3779/j.issn.1009-3419.2017.04.07

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