EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Anaplastic Spindle Cell Squamous Carcinoma Arising from Tall Cell Variant Papillary Carcinoma of the Thyroid Gland: A Case Report and Review of the Literature



Anaplastic Spindle Cell Squamous Carcinoma Arising from Tall Cell Variant Papillary Carcinoma of the Thyroid Gland: A Case Report and Review of the Literature



Case Reports in Endocrinology 2017: 4581626-4581626



Tall cell variant (TCV) of papillary thyroid carcinoma (PTC), an aggressive form of thyroid cancer, is characterised by 50% of cells with height that is three times greater than the width. Very rarely, some of these cancers can progress to spindle cell squamous carcinoma (SCSC) resulting in cancers with elements of both SCSC and TCV PTC. Here we report a case of SCSC arising from TCV PTC. In addition to this case, we have performed a literature review and compiled all published reports of SCSC arising from TCV PTC, including the nature of treatment and the prognosis for each of the 20 patients recorded. This is intended for use as a guide for clinicians in what the most appropriate treatment options may be for a newly diagnosed patient. Due to the rarity coupled with diagnosis occurring at a very advanced stage of disease progression, performing clinical trials is difficult and therefore drawing conclusions on optimal treatment methods remains a challenge.

(PDF same-day service: $19.90)

Accession: 059356890

Download citation: RISBibTeXText

PMID: 28484653

DOI: 10.1155/2017/4581626



Related references

The variable presentations of anaplastic spindle cell squamous carcinoma associated with tall cell variant of papillary thyroid carcinoma. Thyroid 21(5): 493-499, 2011

Anaplastic spindle-cell squamous carcinoma arising in association with tall-cell papillary cancer of the thyroid: A potential pitfall. Diagnostic Cytopathology 21(6): 413-418, 1999

Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection. Genome Research, 2018

Mixed columnar cell and tall cell variant of papillary carcinoma of thyroid: a case report and review of the literature. Pathology 32(4): 286-289, 2001

Spindle cell squamous carcinoma of the thyroid: an unusual anaplastic tumor associated with tall cell papillary cancer. Modern Pathology 4(5): 637-643, 1991

Encapsulated follicular variant of papillary thyroid carcinoma/noninvasive follicular thyroid neoplasm with papillary-like nuclear features with Spindle Cell Metaplasia: Case report and review of literature. Pathology, Research and Practice 213(4): 416-421, 2017

Primary squamous cell carcinoma with its spindle cell variant in the endometrium. A case report and review of literature. Cancer 57(2): 340-345, 1986

Composite Mucoepidermoid Carcinoma and Columnar Cell Variant of Papillary Carcinoma of the Thyroid: A Case Report and Review of the Literature. International Journal of Surgical Pathology 24(4): 336-340, 2016

Anaplastic spindle cell carcinoma, arising in a background of an ovarian mucinous cystic tumor: a case report with clinical follow up, review of the literature. International Journal of Clinical and Experimental Pathology 3(8): 808-811, 2011

Squamous cell carcinoma arising in a papillary carcinoma of the thyroid: a case report. La Tunisie Medicale 85(3): 251-253, 2007

Tall cell variant of papillary carcinoma arising from strumaovarii: a rare case report. Journal of Cancer Research and Therapeutics 9(1): 119-121, 2013

Squamous cell carcinoma arising in a tall cell papillary carcinoma of the thyroid. Journal of Clinical Pathology 58(6): 662-664, 2005

The tall cell variant of papillary carcinoma of the thyroid gland. Comparison with the common form of papillary carcinoma by DNA and morphometric analysis. Archives of Pathology & Laboratory Medicine 115(2): 169-171, 1991

Cutaneous metastasis from anaplastic thyroid carcinoma exhibiting exclusively a spindle cell morphology. A case report and review of literature. Journal of Cutaneous Pathology 43(3): 252-257, 2015

Squamous cell carcinoma of the thyroid: an aggressive tumor associated with tall cell variant of papillary thyroid carcinoma. Modern Pathology 13(7): 742-746, 2000