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A precise termination site in the mouse beta major-globin transcription unit



A precise termination site in the mouse beta major-globin transcription unit



Proceedings of the National Academy of Sciences of the United States of America 80(15): 4694-4698



Nascent labeled RNA from induced, globin-producing mouse erythroleukemia cells was hybridized to cloned regions of the beta major-globin gene. Transcription ceases about 1,000 bases downstream from the poly(A) site as indicated by protection from nuclease digestion of a discrete-sized RNA fragment that it shorter than the protecting cloned DNA fragment. This defines an apparently unique termination site for a protein-coding gene that is transcribed by RNA polymerase II.

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Accession: 059391251

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PMID: 6192441


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