+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Chronic obstructive pulmonary disease and long-term mortality in elderly subjects with chronic heart failure



Chronic obstructive pulmonary disease and long-term mortality in elderly subjects with chronic heart failure



Aging Clinical and Experimental Research 29(6): 1157-1164



Chronic heart failure (CHF) and chronic obstructive pulmonary disease (COPD) are associated with high rates of mortality in elderly subjects. Concurrent CHF and COPD frequently occur, especially in with advancing age. This study examines long-term mortality in community-dwelling elderly subjects affected by CHF alone, COPD alone, and coexistent CHF and COPD. The study evaluated 12-years mortality in 1288 subjects stratified for the presence or absence of CHF or COPD alone, and for coexistence of CHF and COPD. Mortality, at 12 year follow-up, was 46.7% overall, 68.6% in the presence of CHF alone (p < 0.001), 56.9% in the presence of COPD alone (p < 0.01); mortality was 86.2% where CHF and COPD coexisted (p < 0.001) and was significantly higher than in CHF or COPD alone (p < 0.05). Multivariate analysis indicates that CHF (Hazard risk = 1.67, 95% confidence interval 1.15-3.27, p < 0.031) and COPD (Hazard risk = 1.27, 95% confidence interval = 1.08-1.85, p < 0.042) were predictive of long-term mortality. When CHF and COPD simultaneously occurred, the risk dramatically increased up to 3.73 (95% confidence interval = 1.19-6.93, p < 0.001). Long-term follow-up showed higher mortality among elderly subjects affected by CHF or COPD. Simultaneous presence of CHF and COPD significantly increased the risk of death. Therefore, the presence of COPD in CHF patients should be considered a relevant factor in predicting high risk of mortality.

(PDF emailed within 0-6 h: $19.90)

Accession: 059500447

Download citation: RISBibTeXText

PMID: 28224475

DOI: 10.1007/s40520-016-0720-5


Related references

Role of clinical frailty on long-term mortality of elderly subjects with and without chronic obstructive pulmonary disease. Aging Clinical and Experimental Research 23(2): 118-125, 2011

Three-Year Hospitalization and Mortality in Elderly Smokers with Chronic Obstructive Pulmonary Disease or Chronic Heart Failure. Respiration; International Review of Thoracic Diseases: 1-11, 2018

Experiences of long-term life-limiting conditions among patients and carers: what can we learn from a meta-review of systematic reviews of qualitative studies of chronic heart failure, chronic obstructive pulmonary disease and chronic kidney disease?. Bmj Open 6(10): E011694-E011694, 2017

Frailty predicts long-term mortality in elderly subjects with chronic heart failure. European Journal of Clinical Investigation 35(12): 723-730, 2005

Moderate alcohol consumption predicts long-term mortality in elderly subjects with chronic heart failure. Journal of Nutrition, Health & Aging 17(5): 480-485, 2013

Charlson Comorbidity Index does not predict long-term mortality in elderly subjects with chronic heart failure. Age and Ageing 38(6): 734-740, 2010

Waist circumference but not body mass index predicts long-term mortality in elderly subjects with chronic heart failure. Journal of the American Geriatrics Society 58(8): 1433-1440, 2010

Characteristics, treatments and 1-year prognosis of hospitalized and ambulatory heart failure patients with chronic obstructive pulmonary disease in the European Society of Cardiology Heart Failure Long-Term Registry. European Journal of Heart Failure 20(1): 100-110, 2017

Using NT-proBNP to Detect Chronic Heart Failure in Elderly Patients with Chronic Obstructive Pulmonary Disease. Isrn Family Medicine 2013: 273864-273864, 2013

Impact of chronic obstructive pulmonary disease on long-term outcome of patients hospitalized for heart failure. American Journal of Cardiology 101(3): 353-358, 2008

Long-term prognosis of asthma, chronic obstructive pulmonary disease, and asthma-chronic obstructive pulmonary disease overlap in the Copenhagen City Heart study: a prospective population-based analysis. Lancet. Respiratory Medicine 4(6): 454-462, 2017

Acutely decompensated heart failure with chronic obstructive pulmonary disease: Clinical characteristics and long-term survival. European Journal of Internal Medicine: -, 2018

Chronic obstructive pulmonary disease--an independent risk factor for long-term cardiac and cardiovascular mortality in patients with ischemic heart disease. International Journal of Cardiology 143(2): 178-183, 2010

Impact of β-blocker selectivity on long-term outcomes in congestive heart failure patients with chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 10(): 515-523, 2015

BODE index or geriatric multidimensional assessment for the prediction of very-long-term mortality in elderly patients with chronic obstructive pulmonary disease? a prospective cohort study. Age and Ageing 43(4): 553-558, 2015