+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Clinical and Epidemiologic Characteristics of Spreaders of Middle East Respiratory Syndrome Coronavirus during the 2015 Outbreak in Korea



Clinical and Epidemiologic Characteristics of Spreaders of Middle East Respiratory Syndrome Coronavirus during the 2015 Outbreak in Korea



Journal of Korean Medical Science 32(5): 744-749



Nosocomial transmission is an important characteristic of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. Risk factors for transmission of MERS-CoV in healthcare settings are not well defined. During the Korean outbreak in 2015, 186 patients had laboratory-confirmed MERS-CoV infection. Those suspected as a source of viral transmission were categorized into the spreader groups (super-spreader [n = 5] and usual-spreader [n = 10]) and compared to the non-spreader group (n = 171). Body temperature of ≥ 38.5°C (adjusted odds ratio [aOR], 5.54; 95% confidence interval [CI], 1.38-22.30; P = 0.016), pulmonary infiltration of ≥ 3 lung zones (aOR, 7.33; 95% CI, 1.93-27.79; P = 0.003), and a more nonisolated in-hospital days (aOR, 1.32 per 1 day; 95% CI, 1.09-1.60; P = 0.004) were significant risk factors in the spreader group. There was no different clinical factor between super-spreaders and usual-spreaders. Nonisolated in-hospital days was the only factor which tended to be higher in super-spreaders than usual-spreaders (Mean, 6.6 vs. 2.9 days; P = 0.061). Early active quarantine might help reducing the size of an outbreak.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 059505182

Download citation: RISBibTeXText

PMID: 28378546

DOI: 10.3346/jkms.2017.32.5.744


Related references

Survey of Clinical Laboratory Practices for 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea. Annals of Laboratory Medicine 36(2): 154-161, 2016

Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak in South Korea, 2015: epidemiology, characteristics and public health implications. Journal of Hospital Infection 95(2): 207-213, 2017

Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea, 2015. Osong Public Health and Research Perspectives 6(4): 269-278, 2015

An Outbreak of Middle East Respiratory Syndrome Coronavirus Infection in South Korea, 2015. Yonsei Medical Journal 56(5): 1174-1176, 2015

Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015. Emerging Infectious Diseases 22(2): 327-330, 2016

Costly Lessons From the 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in Korea. Journal of Preventive Medicine and Public Health 48(6): 274-276, 2015

An Unexpected Outbreak of Middle East Respiratory Syndrome Coronavirus Infection in the Republic of Korea, 2015. Infection & ChemoTherapy 47(2): 120-122, 2015

Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015. Infection and ChemoTherapy 48(2): 108-117, 2016

Evaluation of a Real-Time Reverse Transcription-PCR (RT-PCR) Assay for Detection of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Clinical Samples from an Outbreak in South Korea in 2015. Journal of Clinical Microbiology 55(8): 2554-2555, 2017

Estimating and modelling the transmissibility of Middle East Respiratory Syndrome CoronaVirus during the 2015 outbreak in the Republic of Korea. Influenza and other Respiratory Viruses 11(5): 434-444, 2017

Risk factors for transmission of Middle East respiratory syndrome coronavirus infection during the 2015 outbreak in South Korea. Clinical Infectious Diseases 64(5): 551-557, 2017

Case characteristics among Middle East respiratory syndrome coronavirus outbreak and non-outbreak cases in Saudi Arabia from 2012 to 2015. Bmj Open 7(1): E011865, 2017

Estimation of basic reproduction number of the Middle East respiratory syndrome coronavirus (MERS-CoV) during the outbreak in South Korea, 2015. Biomedical Engineering Online 16(1): 79, 2017

Implementation of Quaternary Prevention in the Korean Healthcare System: Lessons From the 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea. Journal of Preventive Medicine and Public Health 48(6): 271-273, 2015

Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: a serologic, epidemiologic, and clinical description. Clinical Infectious Diseases 59(9): 1225-1233, 2014