+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Effect of Physical Activity on Self-Reported Disability in Older Adults: Results from the LIFE Study



Effect of Physical Activity on Self-Reported Disability in Older Adults: Results from the LIFE Study



Journal of the American Geriatrics Society 65(5): 980-988



To test the hypothesis that a long-term structured, moderate intensity physical activity (PA) program is more effective than a health education (HE) program in reducing the risk of s elf-reported dependency and disability in basic activities of daily living (BADLs), disability in instrumental ADLs (IADL), and mobility disability. The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, single-blinded randomized trial. University-based research clinic. Thousand six hundred and thirty five sedentary men and women aged 70-89 years, who had functional limitations, defined as a score ≤9 on the Short Physical Performance Battery. Participants were randomized to a structured, moderate intensity PA program (n = 818) that included aerobic, resistance, and flexibility exercises or to a HE program (n = 817). All outcomes were derived by self-report using periodic interviews that asked about the degree of difficulty and receipt of help during the past month. Dependency was defined as "receiving assistance" or "unable" to do ≥1 activities. Disability was defined as having "a lot of difficulty" or "unable" doing ≥1 activities. Severe disability was defined as reporting difficulty or being unable to perform ≥3 activities. Over an average follow-up of 2.6 years, the cumulative incidence of BADL dependency was 15.2% among PA and 15.1% among HE participants (HR = 1.0, 95% CI = 0.78-0.1.3). Intervention groups had similar rates of incident BADL disability, IADL disability and reported mobility disability. Reporting severe mobility disability (HR = 0.78, 95% CI = 0.64-0.96) and ratings of difficulty on mobility tasks were reduced in the PA group. A structured physical activity intervention reduces reported severe mobility disability and difficulty on mobility tasks, but not BADL and IADL disability in older adults with functional limitations.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 059652600

Download citation: RISBibTeXText

PMID: 28168689

DOI: 10.1111/jgs.14742


Related references

Social Participation Modifies the Effect of a Structured Physical Activity Program on Major Mobility Disability Among Older Adults: Results From the LIFE Study. Journals of Gerontology. Series B Psychological Sciences and Social Sciences 73(8): 1501-1513, 2018

Dose of physical activity, physical functioning and disability risk in mobility-limited older adults: Results from the LIFE study randomized trial. Plos one 12(8): E0182155, 2017

Antihypertensive Use and the Effect of a Physical Activity Intervention in the Prevention of Major Mobility Disability Among Older Adults: The LIFE Study. Journals of Gerontology. Series A Biological Sciences and Medical Sciences 71(7): 974-981, 2016

Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA 311(23): 2387-2396, 2014

Is the effect of reported physical activity on disability mediated by cognitive performance in white and african american older adults?. Journals of Gerontology. Series B Psychological Sciences and Social Sciences 64(1): 4, 2009

Physical activity, disability, and quality of life in older adults. Physical Medicine and Rehabilitation Clinics of North America 21(2): 299-308, 2010

Socioeconomic differences in the benefits of structured physical activity compared with health education on the prevention of major mobility disability in older adults: the LIFE study. Journal of Epidemiology and Community Health 70(9): 930-933, 2016

Effects of physical exercise therapy on mobility, physical functioning, physical activity and quality of life in community-dwelling older adults with impaired mobility, physical disability and/or multi-morbidity: a meta-analysis. Ageing Research Reviews 11(1): 136-149, 2012

Physical activity and years of healthy life in older adults: results from the cardiovascular health study. Journal of Aging and Physical Activity 18(3): 313-334, 2010

Cost-effectiveness of the LIFE Physical Activity Intervention for Older Adults at Increased Risk for Mobility Disability. Journals of Gerontology. Series A Biological Sciences and Medical Sciences 71(5): 656-662, 2016

Physical Activity and Performance Impact Long-term Quality of Life in Older Adults at Risk for Major Mobility Disability. American Journal of Preventive Medicine 56(1): 141-146, 2019

Comparative effects of ACE inhibitors and ARBs on response to a physical activity intervention in older adults: results from Lifestyle Interventions for Elders (LIFE) study. Journals of Gerontology. Series A Biological Sciences and Medical Sciences 2019:, 2019

The association of life events and mental ill health in older adults with intellectual disability: results of the wave 3 Intellectual Disability Supplement to The Irish Longitudinal Study on Ageing. Journal of Intellectual Disability Research 63(5): 454-465, 2019

OP26Self-reported frailty components predict incident disability, falls and all-cause mortality in later life: results from a prospective study of older British men. Journal of Epidemiology & Community Health 70(Suppl 1): A19.1-A19, 2016

Cognitive Function as a Predictor of Major Mobility Disability in Older Adults: Results From the LIFE Study. Innovation in Aging 3(2): Igz010, 2019