+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Incidence and influencing factors of continuous positive airway pressure treatment-emergent central sleep apnea in the patients with obstructive sleep apnea syndrome at high altitude



Incidence and influencing factors of continuous positive airway pressure treatment-emergent central sleep apnea in the patients with obstructive sleep apnea syndrome at high altitude



Zhonghua Yi Xue Za Zhi 97(12): 915-919



目的: 调查高原地区阻塞性睡眠呼吸暂停综合征(OSAS)患者初次给予持续气道正压通气(CPAP)后治疗相关的中枢性睡眠呼吸暂停(TE-CSA)的发生率,并分析其人群特征和影响因素。 方法: 回顾分析2015年1—12月来自高原地区(海拔≥1 000 m)并在云南省第一人民医院睡眠医学中心诊断为OSAS的297例成年患者的临床资料,患者均进行了整夜CPAP治疗。根据治疗后是否发生TE-CSA将患者分为TE-CSA组和非TE-CSA组,比较两组的一般资料、居住地海拔、多导睡眠监测及压力滴定参数、肺功能、血气分析等临床数据并进行统计学分析。 结果: 高原地区OSAS患者初次压力滴定时TE-CSA的发生率为16.5%(49/297)。其中男性发生率高于女性(18.2%比6.8%,P=0.061);随着年龄、体质指数(BMI)增加和居住地海拔下降,发生率呈下降趋势。多因素Logistic回归分析显示,居住地海拔高度、混合性呼吸暂停指数(MAI)、第一秒用力呼气容积(FEV(1))/用力肺活量(FVC)比值、肺残气量(RV)/肺总量(TLC)比值是影响TE-CSA发生的主要因素,其中居住地海拔高度、MAI增加是危险因素[OR=1.16(1.02,1.32)、1.05(1.01,1.09)];FEV(1)/FVC、RV/TLC升高则是保护因素[OR=0.94(0.89,0.98)、0.94(0.88,0.99)]。 结论: 高原地区TE-CSA的发生率较高,居住地海拔和MAI增高是其发生的危险因素。.

(PDF emailed within 1 workday: $29.90)

Accession: 059846891

Download citation: RISBibTeXText

PMID: 28355752


Related references

Prevalence of central sleep apnea during continous positive airway pressure (CPAP) titration in subjects with obstructive sleep apnea syndrome at an altitude of 2640 m. Sleep Medicine 16(3): 343-346, 2015

Central sleep apnea on commencement of continuous positive airway pressure in patients with a primary diagnosis of obstructive sleep apnea-hypopnea. Journal of Clinical Sleep Medicine 3(5): 462-466, 2007

Associations Between Sleep Quality, Sleep Architecture and Sleep Disordered Breathing and Memory After Continuous Positive Airway Pressure in Patients with Obstructive Sleep Apnea in the Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep Science 11(4): 231-238, 2019

Central sleep apnea during continuous positive airway pressure therapy in obstructive sleep apnea patients: from the compliance to adaptation, maladaptation and reflexes. Journal of Thoracic Disease 9(11): 4152-4156, 2017

Factors influencing compliance with continuous positive airway pressure ventilation in obstructive sleep apnea syndrome. Tuberkuloz Ve Toraks 60(1): 47-51, 2012

The immediate effects of nasal continuous positive airway pressure treatment on sleep pattern in patients with obstructive sleep apnea syndrome. Electroencephalography & Clinical Neurophysiology 63(1): 10-17, 1986

Increased propensity for central apnea in patients with obstructive sleep apnea: effect of nasal continuous positive airway pressure. American Journal of Respiratory and Critical Care Medicine 181(2): 189-193, 2010

Factors influencing adherence to nasal continuous positive airway pressure in obstructive sleep apnea patients in Japan. Sleep and Biological Rhythms 14(4): 339-349, 2016

Sleep structure correlates of continuous positive airway pressure variations during application of an autotitrating continuous positive airway pressure machine in patients with obstructive sleep apnea syndrome. Chest 121(3): 759-767, 2002

Self-efficacy in sleep apnea: instrument development and patient perceptions of obstructive sleep apnea risk, treatment benefit, and volition to use continuous positive airway pressure. Sleep 26(6): 727-732, 2003

Effect of continuous positive airway pressure treatment on serum cardiovascular risk factors in patients with obstructive sleep apnea-hypopnea syndrome. Chest 132(3): 843-851, 2007

Sleep architecture in the obstructive sleep apnea syndrome with and without nasal continuous positive airway pressure treatment. Federation Proceedings 44(3): 836, 1985

Should sleep laboratories have their own predictive formulas for continuous positive airway pressure for patients with obstructive sleep apnea syndrome?. Journal of the Chinese Medical Association 77(6): 283-289, 2015

Evaluating the sleep quality of obstructive sleep apnea patients after continuous positive airway pressure treatment. Computers in Biology and Medicine 43(7): 870-878, 2014

Frequency of upper airway symptoms before and during continuous positive airway pressure treatment in patients with obstructive sleep apnea syndrome. Respiration; International Review of Thoracic Diseases 80(6): 488-494, 2011