Mycoplasma hyorhinis swine arthritis. II. Morphologic features
Ennis, R.S.; Dalgard, D.; Willerson, J.T.; Barden, J.A.; Decker, J.L.
Arthritis and Rheumatism 14(2): 202-211
ISSN/ISBN: 2326-5191 PMID: 5549969 DOI: 10.1002/art.1780140203
Mycoplasma hyorhinis arthritis, induced in young Yorkshire swine, can be considered as a three-stage process. The first 3 weeks of the disease were characterized by a severe polyserositis and mild synovitis. In the second stage, mononuclear cell infiltration of the synovium and other tissues was apparent. In the final stage, beginning about 3 months after inoculation, lymphocytic aggregates had become nodular, synovial hypertrophy was pronounced, and bone and cartilage destruction by pannus was common. Continued activity was apparent to Day 224.