+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Non-polio Enterovirus detection with acute flaccid paralysis: A systematic review



Non-polio Enterovirus detection with acute flaccid paralysis: A systematic review



Journal of Medical Virology 90(1): 3-7



Acute flaccid paralysis (AFP), as defined by the World Health Organization (WHO), is characterized by an acute onset of limb weakness. In the post-polio era, other enterovirus (EV) serotypes associated with AFP may become more prominent. This study aims to collate the data on the non-polio enteroviruses (NPEV) associated with AFP. A systematic review of published case reports, case series, and surveillance studies of AFP from 1960 through 2017 was undertaken. Data were collected including the country of the study, number of specimens positive for NPEV and available clinical data. The majority of studies originated from Asia. In surveillance studies, EV 71 (a serotype of Enterovirus A) was the most commonly detected serotype with AFP, followed by Enterovirus B serotype echovirus 11 and then Enterovirus B serotype echovirus 11. In case studies and case reports, EV 71 and EV 68 (a serotype of Enterovirus D), were the most commonly detected NPEV. As poliovirus eradication continues, there is a need to ensure that AFP surveillance will also detect other potentially vaccine preventable viruses.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 060025144

Download citation: RISBibTeXText

PMID: 28857219

DOI: 10.1002/jmv.24933


Related references

Characterization of the non-polio enterovirus infections associated with acute flaccid paralysis in South-Western India. Plos one 8(4): E61650, 2013

Characterization of non-polio enterovirus isolates from acute flaccid paralysis children in Pakistan reflects a new genotype of EV-107. Virus Research 170(1-2): 164-168, 2012

Epidemiology and clinical characteristics of acute flaccid paralysis associated with non-polio enterovirus isolation: the experience in the Americas. Bulletin of the World Health Organization 73(5): 597-603, 1995

Typing and identification of non-polio enterovirus from acute flaccid paralysis cases in Ningxia, 1997-2011. Zhonghua Liu Xing Bing Xue Za Zhi 33(11): 1163-1166, 2014

Serotype distribution of non-polio enterovirus in patients with acute flaccid paralysis during 2011-2012 in Hebei Province, China. Bing du Xue Bao 30(1): 33-36, 2014

First detection of enterovirus 71 from an acute flaccid paralysis case with residual paralysis in Iran. Journal of Clinical Virology 42(4): 409-411, 2008

Identification and characterization of nonpolio enterovirus associated with nonpolio-acute flaccid paralysis in polio endemic state of Uttar Pradesh, Northern India. Plos one 14(1): E0208902, 2019

Clinical Features of Acute Flaccid Myelitis Temporally Associated With an Enterovirus D68 Outbreak: Results of a Nationwide Survey of Acute Flaccid Paralysis in Japan, August-December 2015. Clinical Infectious Diseases 66(5): 653-664, 2018

Identification of non polio enteroviruses isolated from selected acute flaccid paralysis (AFP) stool samples in the Ghana polio regional reference laboratory: Implication for causative agents to AFP other than polio. 2007

Detection of non-polio enteroviruses from 17 years of virological surveillance of acute flaccid paralysis in the Philippines. Journal of Medical Virology 84(4): 624-631, 2012

Comparison of cell culture with RT-PCR for enterovirus detection in stool specimens from patients with acute flaccid paralysis. Journal of Clinical Laboratory Analysis 21(4): 232-236, 2007

Characterization of a novel enterovirus serotype and an enterovirus EV-B93 isolated from acute flaccid paralysis patients. Plos one 8(11): E80040, 2013

Correlation between Non-Polio Acute Flaccid Paralysis Rates with Pulse Polio Frequency in India. International Journal of Environmental Research and Public Health 15(8):, 2018

Non-polio enteroviruses in acute flaccid paralysis children of India: vital assessment before polio eradication. Journal of Paediatrics and Child Health 45(7-8): 409-413, 2009

Serum IgG and IgA levels in polio and non-polio acute flaccid paralysis cases in western Uttar Pradesh, India. Indian Pediatrics 52(3): 220-222, 2015